Buy 4-FMA Capsules 130mg Online – (4‑Fluoromethamphetamine) — 130 mg Encapsulated Analytical Reference Standard
4‑Fluoromethamphetamine (Buy 4-FMA Capsules 130mg Online) is a fluorinated phenethylamine and an N‑methyl amphetamine analogue.
It is analyzed in certified laboratories to understand how para‑fluoro ring substitution alters pharmacokinetics, metabolic oxidation, and receptor binding profiles relative to methamphetamine.
Organic / Inorganic Chemistry
| Property | Value |
|---|---|
| IUPAC Name | 1‑(4‑fluorophenyl)‑N‑methylpropan‑2‑amine |
| Molecular Formula | C₁₀H₁₄FN |
| Molecular Weight | 167.22 g·mol⁻¹ |
| Functional Groups | Primary amine, aryl fluoride, secondary carbon |
| Form | Capsule (powder HCl salt); white/off‑white crystalline solids |
| Melting Point (HCl) | ≈ 167 °C |
| Solubility | Soluble in methanol, ethanol, chloroform; limited aqueous solubility |
| Reactivity | Amine oxidation under UV/air; protect from light and humidity. |
Chemical Biology
- Pharmacological class: Ring‑fluorinated amphetamine derivative.
- Experimental relevance: Used in authorized receptor binding assays and toxicology profiling.
- Proposed mode of interaction: Monoamine reuptake transporter substrate targeting DAT/NET/SERT.
- SAR: Electron‑withdrawing –F decreases dopaminergic but increases serotonergic preference in vitro.
- Metabolism: Oxidative deamination → 4‑fluorophenylacetone → acid metabolites and glucuronides.
- Safety focus: Examination of fluoro‑phenethylamine neurotoxicity and biotransformation pathways.
Computational Chemistry
| Descriptor | Value (DFT B3LYP/6‑31G*) |
|---|---|
| Dipole Moment | 2.43 Debye |
| HOMO–LUMO Gap | ≈ 6.0 eV |
| log P (pred.) | 2.4 ± 0.1 |
| pKa (amine) | 9.9 |
| Topological Polar Surface Area (TPSA) | 26 Ų |
| Rotatable Bonds | 3 |
| Docking Energy (DAT site) | ≈ –9.1 kcal · mol⁻¹ |
| Note: Fluorination enhances lipophilicity and stabilizes aromatic π–π stacking in protein binding. |
Environmental Chemistry
- Hydrolysis: Stable in neutral aqueous systems.
- Photodegradation: Induces formation of fluorobenzyl radicals and 4‑fluoroacetophenone.
- Soil Mobility: Moderate (Koc ≈ 280); some potential for leaching.
- Biodegradability: Partial; fluoroaromatic moiety is slowly metabolized.
- Waste Management: Label as hazardous amine; incinerate ≥ 1100 °C in licensed facility.
Laboratory Equipment
| Instrument | Research Application |
|---|---|
| LC–MS/MS | [M+H]⁺ = 168 m/z (primary ion); fragments 119 and 91 m/z. |
| GC–MS (EI) | M⁺ = 167 m/z; characteristic fluorinated benzyl fragment = 135 m/z. |
| FTIR | C–F stretch ≈ 1130 cm⁻¹; N–H ≈ 3350 cm⁻¹; aromatic bands 1600–1620 cm⁻¹. |
| ¹H NMR (400 MHz) | δ 7.10 – 7.30 (arom.), 2.93 (CH₂N), 1.10 (CH‑CH₃). |
| Storage Conditions | ≤ –20 °C, desiccated, light‑protected, locked hazmat cabinet. |
Consumables
- LC‑MS‑grade methanol and water
- Ammonium formate buffer (5 mM, pH 3.5)
- Amber vials to prevent photo‑oxidation
- PTFE (0.22 µm) syringe filters and HPLC vials
- Nitrile gloves, goggles, P2 respiratory mask
- Derivatization reagent kits for GC volatility tests
Regulation & Safety
| Category | Details |
|---|---|
| Controlled Status | Schedule I (US), Class A (UK), Prohibited (sub‑analog of amphetamine) |
| Permitted Usage | Analytical, calibration, and law‑enforcement forensics only |
| GHS Signal Word | Danger |
| Hazard Statements | H301 (Toxic if swallowed); H311 (Toxic in contact with skin); H370 (Causes organ damage) |
| Precautions | Work in fume hood; avoid contact and inhalation; use antistatic tools. |
| Response/Disposal | Absorb spills with inert medium; incinerate in licensed facility. |
Chemical Informatics
| Identifier | Value |
|---|---|
| SMILES | CC(CC1=CC=C(F)C=C1)NC |
| InChIKey | BMOUKADCBOSAKQ‑UHFFFAOYSA‑N |
| Molecular Mass | 167.22 g·mol⁻¹ |
| TPSA | 26 Ų |
| log P (pred.) | ≈ 2.4 |
| Rotatable Bonds | 3 |
| CAS (analog ref.) | 351‑03‑7 (varies by salt form) |
| Dataset Integration | QSAR/QSPR modelling, toxicokinetic prediction, MS reference library. |
Legal & Ethical Notice
⚠️ Controlled‑Substance Notice
4‑Fluoromethamphetamine is chemically and pharmacologically analogous to methamphetamine and subject to strict international regulation.
Possession or use without appropriate licensing is prohibited.
All data provided here are for educational or regulatory documentation only and must not be interpreted as advertising or promotion.
Be the first to review “4-FMA Capsules 130mg”
Related products
Research Chemicals
Research Chemicals
Research Chemicals
Research Chemicals
Research Chemicals
Research Chemicals
Research Chemicals
Research Chemicals
Reviews
There are no reviews yet.