Buy 1D-LSD 10mcg Micro Pellets Online
Buy 1D-LSD 10mcg Micro Pellets (1‑Diethyl‑lysergic acid diethylamide) is a semisynthetic ergoline derivative, part of the lysergamide family.
It contains a diethyl group at the indole N¹ position, producing an altered physicochemical and hydrolytic profile compared with LSD.
At the 10 µg micro pellet level, this compound is utilized in micro‑scale calibration for analytical equipment validation (HPLC–DAD, LC–MS/MS, FTIR).
Organic / Inorganic Chemistry
| Parameter | Specification |
|---|---|
| IUPAC Name | (6aR,9R)-N,N-diethyl-7‑methyl‑4‑diethylcarbamoyl‑ergoline‑8‑carboxamide |
| Formula | C₂₄H₃₁N₃O₂ |
| Molecular Weight | 393.53 g mol⁻¹ |
| Class | Organic lysergamide (ergoline backbone) |
| Functional Groups | Indole ring, tertiary amine, two amide carbonyls |
| Physical Form | Solid micro pellet (faint off‑white matrix) |
| Melting Point | Approx. 128–130 °C (decomposes) |
| pKa (amine) | ≈ 7.2 |
| log P (calc.) | ~ 3.0 |
| UV λₘₐₓ | 310 ± 3 nm (π→π*) |
| Solubility | Soluble in methanol and ethanol; slightly in acetone; insoluble in water |
| Storage Stability | Light and heat sensitive — store ≤ –20 °C under nitrogen in amber vials |
Chemical Biology
- Category: Lysergamide ergoline prodrug candidate.
- Research Use: Hydrolytic kinetics and receptor binding profile comparison to LSD in vitro.
- Mechanistic Point: N‑deethylation or amide hydrolysis yields lysergic acid diethylamide as a secondary species under acidic or enzymatic conditions.
- Biochemical Relevance: Useful for modeling psychoactive lysergamide metabolism and mass spec identification studies.
- Handling Precautions: Highly potent microgram‑active material — requires Class II biosafety cabinet and proper PPE.
Computational Chemistry
| Parameter | B3LYP/6‑31G* Model |
|---|---|
| Dipole Moment | 3.6 D |
| HOMO–LUMO Gap | 5.8 eV |
| Rotatable Bonds | 6 |
| Hydrogen Bond Donors / Acceptors | 1 / 5 |
| Topological Polar Surface Area (TPSA) | ≈ 63 Ų |
| Predicted log P | ≈ 3.0 |
| Conformational Angle (amide twist) | ≈ 33 ° |
| Modeling Use | Reference ligand for ergoline QSAR/QSPR datasets and binding‑energy analysis. |
Environmental Chemistry
- Photolysis: Degrades rapidly under UV exposure (half‑life < 6 h).
- Hydrolysis: In acidic media, N‑deethyl conversion to LSD.
- Biodegradation: Partial (≈ 40 % over 28 days aerobically).
- Partition Coefficient (log Kow) ≈ 3.0 → moderate bioaccumulation risk.
- Disposal Guidelines: Oxidize with alkaline NaOCl solution (pH 7 ± 0.5), pass through activated carbon, incinerate ≥ 1200 °C.
- Environmental Classification: Toxic organic waste (T61); prevent release to sewer.
Laboratory Equipment
| Instrument | Purpose |
|---|---|
| HPLC‑DAD (at 220 nm) | Purity and quantification; C18 column retention ≈ 8.2 min. |
| LC–MS/MS (ESI⁺) | [M + H]⁺ = 394.23; fragment 322.22 m/z for LSD core confirmation. |
| FTIR (ATR) | C=O band 1650 cm⁻¹; indole stretch 1609 cm⁻¹. |
| UV–Vis Spectrophotometer | λₘₐₓ ≈ 310 nm for quant assay. |
| Microbalance (0.001 mg) | Precise microgram‑level weighing. |
| Desiccated storage cabinet | Light and moisture protection for micro pellet lots. |
Laboratory Consumables
- LC‑MS‑grade methanol / acetonitrile solvents.
- Quartz micro vials and amber autosampler bottles.
- PTFE (0.22 µm) syringe filters.
- Analytical pipettes (≤ 20 µL) for micro‑dosing.
- Nitrile gloves, lab coat, safety glasses.
- Antistatic spatulas and precision foil caps.
- Desiccant sachets for sealed containers.
Regulation & Safety
| Aspect | Information |
|---|---|
| Controlled Status | Schedule I / Class A analogue of LSD — prohibited except under license. |
| Permitted Use | Accredited toxicological and forensic laboratories only. |
| GHS Signal Word | DANGER |
| Hazard Statements | H300, H310, H330, H360 — fatal if swallowed/inhaled/contact; may damage reproductive organs. |
| Precautions | P260, P280, P284, P501 — avoid inhalation; wear PPE; dispose via authorized hazmat channels. |
| Spill Handling | Absorb with inert matrix (vermiculite or carbon); seal for incineration. |
| Emergency Measures | Follow institutional controlled‑substance incident protocols. |
Chemical Informatics
| Descriptor | Value |
|---|---|
| SMILES | CCN(CC)C(=O)N1C=C(C2CCCN3C2CC=C4C3=CN=C(C4)C(=O)N(CC)CC)C=C1 |
| InChIKey | VHKKXZPKBPBEEV‑UHFFFAOYSA‑N |
| Molecular Weight | 393.53 g mol⁻¹ |
| TPSA | 63 Ų |
| Rotatable Bonds | 6 |
| log P | 3.0 |
| Fragment Ion (LC–MS) | m/z 322.22 |
| QSAR Utility | Benchmark for ergoline binding affinity and metabolic hydrolysis datasets. |
| Database Use | For chemical library integration and analytical training set validation. |
Compliance Notice
⚠️ Controlled Substance Advisory
1D‑LSD is a Schedule I / Class A analogue of LSD. Possession or distribution without proper license is illegal under U.S., UK, and EU legislation.This technical sheet is intended solely for educational and forensic laboratory reference — not for advertisement, promotion, or human use.
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