Buy 1P-LSD 150mcg Art Blotters Online
1P-LSD 150mcg Art Blotters (1‑propionyl‑lysergic acid diethylamide) is a substituted ergoline belonging to the lysergamide chemical class.
It acts as a N‑propionyl derivative of LSD, serving as a model compound to study prodrug mechanisms, analytical detection methods, and stability kinetics in controlled chemical environments.
The 150 µg art blotter format denotes a regulated micro‑dosage matrix suitable for quantitative instrument calibration and trace substance identification.
Organic / Inorganic Chemistry
| Parameter | Value |
|---|---|
| IUPAC Name | (6aR,9R)‑N,N‑diethyl‑7‑methyl‑4‑propionamido‑1‑propionyl‑ergoline‑8‑carboxamide |
| Chemical Formula | C₂₃H₂₉N₃O₂ |
| Molar Mass | 379.50 g/mol |
| Functional Groups | Indole, amide (×2), tertiary amine |
| Physical State | Paper embedded organic solid |
| UV Absorption | 308 nm (π→π* transition) |
| Melting Point (decomp.) | ≈ 127 °C |
| Log P (calc.) | 2.9 |
| pKa (amine) | 7.3 |
| Solubility | Soluble in MeOH/Ethanol; low in water |
| Storage Stability | Sensitive to UV and humidity; store ≤ –20 °C, dark, dessicated |
Chemical Biology
- Bio‑class: Lysergamide prodrug of LSD.
- Scientific use: Study of enzymatic cleavage mechanisms (N‑depropionylation) and receptor binding modelling.
- In vitro activity: Hydrolysis at N¹ releases LSD and propionic acid.
- Toxicology: Nanogram‑level biopotency; handled only in contained BSL‑2 analytical labs.
- Pharmacokinetic interest: Model compound for pro‑drug release rate predictions.
Computational Chemistry
| Property | B3LYP/6‑31G* Estimate |
|---|---|
| Dipole Moment | 3.7 D |
| HOMO–LUMO Gap | 5.9 eV |
| Rotatable Bonds | 6 |
| Polar Surface Area (TPSA)** | 62 Ų |
| log P | ~2.9 |
| Hydrogen Bond Donors / Acceptors | 1 / 5 |
| Conformation | Planar ergoline core with amide torsion ≈ 34° |
| Computational Use** | QSAR/QSPR datasets for lysergamide series and prodrug hydrolysis rates |
Environmental Chemistry
- Photostability: Degrades under UV light (half‑life < 6 h).
- Hydrolysis: Hydrolyzes to LSD + propionic acid at acidic pH.
- Biodegradation: Partially biodegradable (~40 % after 28 days, aerobic conditions).
- Partition Coefficient (log Kow): ~2.9 — moderately hydrophobic.
- Waste Disposal Method: Oxidative neutralization or incineration ≥ 1200 °C.
- Environmental Risk: Listed as toxic organic solid; do not release into environment.
Laboratory Equipment
| Instrument | Purpose |
|---|---|
| LC‑MS/MS (ESI⁺) | [M + H]⁺ = 380.22 → 322.22 m/z — confirms LSD fragment signature. |
| HPLC‑DAD (220 nm) | Retention ~ 7.9 min (C18 60:40 MeCN/H₂O + 0.1 % FA). |
| FTIR (ATR) | Amide C=O stretch 1655 cm⁻¹; indole bands 1610 cm⁻¹. |
| UV–Vis Spectrophotometer | Calibration λ ≈ 308 nm for quantification. |
| High‑precision balance (0.001 mg) | Reference standard dilution preparation. |
| Dark‑room storage | Prevents photolytic decomposition of blotters. |
Laboratory Consumables
- LC‑MS‑grade methanol, acetonitrile, water.
- Amber autosampler vials with PTFE seals.
- PTFE syringe filters (0.22 µm).
- Desiccant‑lined containers for humidity control.
- PPE: nitrile gloves, lab coat, protective glasses, respirator if dust risk exists.
- Antistatic work surface mats for microgram mass handling.
Regulation & Safety
| Aspect | Details |
|---|---|
| Legal Status | Schedule I / Class A analogue of LSD (EU, UK, US). |
| Permitted Use | Licensed forensic and academic research only. |
| Signal Word (GHS) | Danger |
| Hazard Statements | H301 · H311 · H331 · H360 — Fatal if ingested or inhaled; possible reproductive toxicant. |
| Precautionary Statements | P260, P280, P284, P501 — Use respiratory protection; dispose via hazardous waste contractor. |
| Emergency Spill Control | Absorb with activated carbon or vermiculite; seal for licensed incineration. |
| UN Transport Code | UN 3462 (Organic toxic solid, n.o.s.) |
Chemical Informatics
| Descriptor | Value |
|---|---|
| SMILES | CCC(=O)N1C=C(C2CCCN3C2CC=C4C3=CN=C(C4)C(=O)N(CC)CC)C=C1 |
| InChIKey | KDXQNBOJNSEWHS‑UHFFFAOYSA‑N |
| Molecular Mass | 379.50 g/mol |
| TPSA | 62 Ų |
| Rotatable Bonds | 6 |
| log P | 2.9 |
| PubChem CID | 137964585 |
| ChemSpider ID | 78619960 |
| Database Use | Standard for lysergamide QSAR model training and prodrug activation prediction. |
Compliance Notice
⚠️ Controlled Substance Advisory
1P‑LSD is classified as a controlled psychoactive analog of LSD under Schedule I (US) and Class A (UK / EU).
Possession, sale, or distribution outside licensed laboratory settings is prohibited.This reference entry is provided solely for educational and forensic use, not for promotion or administration to humans.
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