Buy 1cP-LSD 20mcg Micro Blotters Online
Buy 1cP-LSD 20mcg Micro Blotters is a semi‑synthetic ergoline (lysergamide) featuring a cyclopropionyl substitution at the indole‑N¹ position of LSD.
It functions as a hydrolysis‑labile derivative that can be used as an analytical reference standard for LSD‑type compounds.
The 20 µg micro blotter enables trace‑tier calibration, instrumental validation, and forensic differentiation studies of lysergamide analogues.
Organic / Inorganic Chemistry
| Parameter | Data |
|---|---|
| IUPAC Name | (6aR,9R)‑N,N‑diethyl‑7‑methyl‑4‑(1‑cyclopropanecarboxamido)‑ergoline‑8‑carboxamide |
| Chemical Formula | C₂₄H₃₁N₃O₂ |
| Molecular Mass | 393.52 g·mol⁻¹ |
| Functional Groups | Indole core, amide ×2, tertiary amine |
| Physical Form | Impregnated cellulose blotter (matrix solid) |
| Melting Point (decomp.) | ≈ 126 °C |
| Solubility | Soluble in EtOH / MeOH; slightly soluble in acetone; insoluble in water |
| pKa (amine) | 7.4 |
| log P (calc.) | ≈ 2.9 |
| UV λₘₐₓ | ∼ 308 nm |
| Storage Stability | Light‑sensitive; store ≤ –20 °C in amber containers |
Chemical Biology
- Category: Lysergamide ergoline; N¹‑cyclopropanoyl LSD analogue.
- Research Applications: Hydrolytic prodrug mechanistic studies; used for method verification of lysergamide screening.
- Biochemical Significance: Hydrolyzes to LSD under acidic or enzymatic conditions in simulated biological models.
- Utility: Differentiation of LSD analogs in LC‑MS forensic fingerprinting.
- Hazard Note: Extremely potent ergoline — handle only in Class II biosafety cabinets with category‑3 PPE.
Computational Chemistry
| Parameter | DFT ( B3LYP/6‑31G* ) |
|---|---|
| Dipole Moment | 3.4 D |
| HOMO–LUMO Gap | 5.9 eV |
| Rotatable Bonds | 6 |
| Hydrogen Bond Donors / Acceptors | 1 / 5 |
| Topological Polar Surface Area (TPSA) | 61 Ų |
| Predicted log P | 2.9 |
| Conformational Detail | Cyclopropyl‑amide twist ≈ 32 °; planar indole aromaticity preserved. |
| Computational Application | Ligand conformational analysis and ergoline binding model training datasets. |
Environmental Chemistry
- Photostability: Decomposes rapidly under UV — half‑life < 5 hours in air light.
- Hydrolysis Behavior: Acidic medium → LSD and cyclopropionic acid.
- Biodegradability: Partial mineralization (30–40 % in 28 days aerobically).
- Partition Coefficient (log Kow): 2.9 — moderate lipophilicity.
- Waste Management: Destroy via oxidative digestion (alkaline NaOCl solution pH 7–8) and incineration ≥ 1200 °C.
- Environmental Risk: Do not release to waterways — classified as hazardous organic waste.
Laboratory Equipment
| Instrument | Use |
|---|---|
| LC–MS/MS (ESI⁺) | [M + H]⁺ = 394.23 m/z; fragment 322.22 m/z → LSD core signature. |
| HPLC–DAD (220 nm) | Retention ≈ 7.8 min on C18 column. |
| GC–MS (EI) | Distinct M⁺ fragment pattern for cyclopropanoyl substitution. |
| FTIR (ATR) | Amide C=O band 1653 cm⁻¹; indole stretch 1609 cm⁻¹. |
| UV–Vis Spectrophotometer | Peak absorbance ≈ 308 nm — quant determination. |
| Precision Balance (0.001 mg) | Microdose verification of blotter loads. |
Laboratory Consumables
- LC‑MS‑grade solvents (MeOH, ACN, H₂O ≥ 18 MΩ·cm).
- Amber HPLC vials with PTFE/silicone caps.
- 0.22 µm PTFE syringe filters.
- Microliter pipettes for trace solutions.
- Nitrile gloves, safety glasses, protective lab coat.
- Antistatic tweezers for micro blotter manipulation.
- Desiccant packs for sealed containers.
Regulation & Safety
| Aspect | Information |
|---|---|
| Controlled Status | Schedule I / Class A lysergamide analogue (in EU, US, UK). |
| Authorized Use | Research and forensic testing within licensed facilities. |
| GHS Signal Word | DANGER |
| Hazard Statements | H300 · H310 · H330 · H360 — Fatal if ingested, inhaled, or skin contact; may damage reproductive organs. |
| Precautions | P260 · P280 · P284 · P501 — Use within fume hood / biosafety cabinet; wear proper PPE and dispose as hazardous waste. |
| Spill Procedure | Neutralize with activated carbon; avoid aerosolization; collect for incineration. |
| Transport Reference | UN 3462 — “Toxic solid, organic, n.o.s.” (Regulated Transport Class 6.1). |
Chemical Informatics
| Descriptor | Data |
|---|---|
| SMILES | CCN(CC)C(=O)N1C=C(C2CCCN3C2CC=C4C3=CN=C(C4)C(=O)N1C1CC1)C=C1 |
| InChIKey | ULNYVTXZJYTXBH‑UHFFFAOYSA‑N |
| Molecular Weight | 393.52 g·mol⁻¹ |
| TPSA | 61 Ų |
| Rotatable Bonds | 6 |
| Predicted log P | ≈ 2.9 |
| Database Utility | QSAR training entry for ergoline binding affinity and metabolic pathway datasets. |
| Primary LC–MS Transition (m/z) | 394.23 → 322.22 (LSD core ion). |
Compliance Notice
⚠️ Regulatory Advisory
1cP‑LSD is a Schedule I / Class A controlled substance analogue. Possession, distribution, or use outside licensed laboratory authority is illegal in most jurisdictions.This document is intended for educational and forensic reference only — not for human use or commercial promotion.
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