Buy 2‑FEA Pellets 60mg Online — Analytical Reference Standard
Buy 2‑FEA Pellets 60mg (2‑fluoroethylamphetamine) is a fluoro‑substituted ethylamphetamine derivative belonging to the β‑phenethylamine class.
It is used in forensic toxicology, reference standard calibration, and computational SAR research investigating the impact of fluorine substitution on physicochemical and receptor‑binding properties.
Pelletized 60 mg aliquots allow accurate dosage handling for analytical workflows and instrument calibration.
Organic / Inorganic Chemistry
| Parameter | Specification |
|---|---|
| IUPAC Name | 1‑(2‑fluorophenyl)‑2‑ethylamine |
| Molecular Formula | C₁₀H₁₄FN |
| Molecular Weight | 167.22 g mol⁻¹ |
| Chemical Class | Fluoro‑substituted amphetamines |
| Functional Groups | Aromatic ring (–F substituent), secondary amine, ethyl chain |
| Physical State | White–off‑white compressed pellets (60 mg nominal) |
| pKa (amine) | ≈ 9.7 |
| log P (pred.) | ≈ 2.2 |
| Melting Point | ≈ 175 °C |
| Boiling Point (free base) | ≈ 227 °C |
| Storage Conditions | ≤ –20 °C · dry · sealed in amber container |
| Analytical Purity | ≥ 99 % (assayed by HPLC / MS ) |
Chemical Biology
- Pharmacological Type: Amphetamine‑class monoamine releasing agent.
- Research Application: Benchmark molecule for fluorine‑induced alterations in neurotransmitter transporter binding affinity.
- Mechanistic Note: Interacts with dopamine and norepinephrine transporters in vitro; used for computational simulation of binding energy changes vs methamphetamine analogues.
- Toxicology: Central nervous system stimulant; microgram‑scale handling requires BSL‑2 controls.
- Biosafety Guidelines: Full PPE and Class A controlled substance procedures mandatory.
Computational Chemistry
| Descriptor | B3LYP/6‑31G* Predicted Value |
|---|---|
| Dipole Moment | 2.76 D |
| HOMO–LUMO Gap | 5.78 eV |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| TPSA | 32 Ų |
| log P (calc.) | 2.2 |
| DAT Binding Energy (in silico)** | –8.9 kcal·mol⁻¹ |
| NET/SERT Binding Energy (in silico)** | –8.3 kcal·mol⁻¹ |
| QSAR Value** | Comparative reference for ortho‑fluoro vs non‑fluoro ethamphetamine ligands. |
Environmental Chemistry
- Persistence: Stable under neutral pH and ambient conditions.
- Volatility: Low; vapor pressure ≈ 1 × 10⁻⁵ mm Hg (20 °C).
- Photodegradation Half‑Life: ≈ 6 h at 355 nm UV‑A.
- Partition Coefficient (log Kow): ≈ 2.2 → low bioaccumulation predicted.
- Degradation By‑products: 2‑fluorophenylacetone and fluorobenzoic acid under oxidative conditions.
- Waste Treatment: Ozone / UV advanced oxidation process (AOP) or ≥ 1100 °C thermal incineration in licensed facility.
Laboratory Equipment
| Device | Analytical Use |
|---|---|
| LC–MS/MS (ESI⁺) | [M + H]⁺ = 168 m/z → fragments 150 and 119 m/z |
| GC–MS (EI) | Characteristic ions: 167 m/z (M⁺), 44 m/z (base peak) |
| FTIR (ATR) | C–F stretch ~ 1100 cm⁻¹, N–H stretch 3300 cm⁻¹ |
| ¹H NMR (CDCl₃) | δ 7.0–7.3 (aromatic H), 2.8 (N‑CH₃), 1.1 (ethyl CH₃) |
| HPLC Method | C18, ACN:H₂O (60:40, 0.1 % FA), Rt ≈ 4.2 min |
Laboratory Consumables
- LC–MS grade methanol, acetonitrile and water.
- Amber autoinjector vials with PTFE septa.
- Precision pipettes and Class A volumetric flasks.
- PTFE membrane filters (0.22 µm).
- Certified microbalances (± 0.01 mg) and anti‑static weighing paper.
- PPE: chemical‑resistant nitrile gloves, safety goggles, lab coat, respiratory protection /fume hood use.
Regulation & Safety
| Aspect | Guideline |
|---|---|
| Legal Status | Controlled substance analogue (Formally Schedule I/Class A territories). |
| Regulatory Use | Permitted exclusively under forensic or research license. |
| GHS Signal Word | Danger |
| Hazard Statements | H301 · H311 · H331 — Toxic if swallowed, inhaled, or on skin contact. |
| Precautionary Statements | P260 · P280 — Avoid inhalation; wear protective equipment. |
| First‑Aid Measures | Immediate medical attention; symptomatic treatment only. |
| Waste Disposal | High‑temperature incineration ≥ 1100 °C via licensed hazardous waste disposal route. |
Chemical Informatics
| Field | Reference |
|---|---|
| SMILES | CC(CC1=CC=CC=C1F)NC |
| InChIKey | OZPYKEIVIHODQM‑UHFFFAOYSA‑N |
| Molecular Mass | 167.22 g mol⁻¹ |
| TPSA | 32 Ų |
| Rotatable Bonds | 3 |
| CAS Reference | N/A (unregistered psychoactive analogue). |
| Database Links | ChemSpider Ref. 55386749 · PubChem CID 118796970 |
| QSAR Role | Reference compound for fluorine substitution in ethylamphetamine series. |
Compliance Notice
⚠️ Controlled Substance Advisory
2‑Fluoroethylamphetamine (2‑FEA) and its salts are controlled amphetamines (Schedule I/Class A) in most jurisdictions.
Possession or distribution is prohibited except for licensed forensic and academic institutions.
Information here is presented solely for educational and regulatory reference, not for marketing or consumption.




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