LGD-4033 Powder (Ligandrol)

Buy LGD-4033 Powder (Ligandrol) Online

Buy LGD-4033 Powder, commonly known as Ligandrol, is a nonsteroidal, orally active selective androgen receptor modulator (SARM) under investigation for its potential in treating muscle wasting conditions. It is available in powder form and is intended strictly for scientific research and analytical purposes.

Chemical Composition and Properties

• Chemical Name: 4-[(2R)-2-[(1R)-2,2,2-Trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile
• Molecular Formula: C₁₄H₁₂F₆N₂O
• Molecular Weight: 338.25 g/mol
• CAS Number: 1165910-22-4
• Appearance: White to off-white crystalline powder
• Solubility: Soluble in DMSO; limited solubility in water
• Storage Conditions: Store at room temperature in a dry environment; for extended stability, store at -20°C

These properties are crucial for researchers to consider when designing experiments and handling the compound.

Mechanism of Action

LGD-4033 functions as a selective agonist of the androgen receptor (AR), exhibiting high affinity and specificity. By binding to ARs, it stimulates anabolic activity in muscle and bone tissues while minimizing androgenic effects in other tissues. This selectivity is achieved through its nonsteroidal structure, which allows for tissue-specific activation of ARs.

Laboratory Equipment and Consumables

When conducting research with LGD-4033 powder, it’s essential to utilize appropriate laboratory equipment and consumables to ensure accurate and safe experimentation. This includes:

• Precision balances for weighing
• Solvent-resistant containers for dissolution
• Personal protective equipment (PPE) such as gloves and safety goggles
• Proper storage solutions, like desiccators and temperature-controlled environments, to maintain the compound’s stability

Regulation and Safety

LGD-4033 is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes. Researchers using it in laboratory contexts should observe:

• Protective equipment when handling powders
• Proper ventilation and storage per Material Safety Data Sheet (MSDS) guidelines
• Careful documentation of doses and observations
• Monitoring for any adverse effects if used in controlled animal studies

Proper disposal of LGD-4033 and related materials is crucial to prevent environmental contamination. Laboratories should adhere to local regulations regarding hazardous waste disposal. This includes:

• Neutralizing solutions
• Using designated waste containers
• Contracting certified disposal services

Chemical Informatics

Utilizing chemical informatics tools can aid researchers in understanding LGD-4033’s properties, interactions, and potential applications. Databases such as PubChem provide comprehensive information on chemical structures, biological activities, safety, and toxicity data. These resources are invaluable for designing experiments and predicting outcomes.

Conclusion

LGD-4033 powder offers a promising avenue for research into selective androgen receptor modulators and their mechanisms of action. However, due to its potent biological activity and regulatory status, it is imperative that researchers handle this compound with caution, adhere to safety protocols, and stay informed about legal considerations.