Buy 1D-LSD 150mcg Blotters Online
Buy 1D-LSD 150mcg Blotters is a synthetic ergoline lysergamide featuring a diethyl substitution on the indole nitrogen (N¹) of the LSD skeleton.
This structural modification subtly alters its physicochemical properties (lipophilicity, metabolic hydrolysis rate), making it valuable as a reference analyte for analytical validation and QSAR correlation in controlled‑substance research.
The blotter format (150 µg per unit) enables trace calibration and method validation for chromatographic and spectrometric analysis.
Organic / Inorganic Chemistry
| Parameter | Specification |
|---|---|
| IUPAC Name | (6aR,9R)‑N,N‑diethyl‑7‑methyl‑4‑diethylcarbamoyl‑ergoline‑8‑carboxamide |
| Formula | C₂₄H₃₁N₃O₂ |
| Molar Mass | 393.53 g mol⁻¹ |
| Functional Groups | Indole aromatic, tertiary amine, amide × 2 |
| Physical Appearance | Paper substrate (blotter) with color‑stable organic coating |
| Melting Point (decomp.) | ~ 128 °C |
| Log P (calc.) | ≈ 3.0 |
| pKa (amine) | 7.2 |
| Solubility Profile | Moderate in MeOH / EtOH; low in aqueous solution |
| UV λₘₐₓ | ≈ 310 nm |
| Storage Stability | UV‑ and moisture‑sensitive; store ≤ –20 °C in amber containers |
Chemical Biology
- Family: Lysergamide ergoline pro‑drugs.
- Laboratory research role: Used to study hydrolytic pathways to LSD and related metabolites.
- Mechanism of interest: Enzymatic and non‑enzymatic N‑de‑diethylation in simulated biological systems.
- Assay applications: Reference for LSD immunoassay false‑positive investigations; LC‑MS fragmentation predictor.
- Toxicological remarks: Nanomolar potency — must be handled within certified Class II biosafety cabinet.
Computational Chemistry
| Parameter | DFT (B3LYP/6‑31G*) Estimation |
|---|---|
| Dipole Moment | 3.6 D |
| HOMO‑LUMO Gap | 5.8 eV |
| Hydrogen‑Bond Donors / Acceptors | 1 / 5 |
| Rotatable Bonds | 6 |
| Topological Polar Surface Area | ≈ 63 Ų |
| Predicted log P | 3.0 |
| Conformational Feature** | Ergoline core planarity + amide torsion ≈ 33° |
| Computation Purpose** | Docking and QSAR/QSPR illustration in ergoline series datasets |
Environmental Chemistry
- Photostability: Degrades within hours under UV light; keep light‑protected.
- Hydrolysis: Gradual conversion to LSD and diethylamine derivatives in aqueous acidic media.
- Biodegradability: Partial (~40 % after 28 days in aerobic soil conditions).
- Octanol‑Water Partition (log Kow): Approx. 3.0 — moderately hydrophobic.
- Waste Treatment: Chemical oxidation or thermal incineration ≥ 1200 °C.
- Environmental Hazard: Do not discharge into drains — dispose through licensed hazardous‑waste channel.
Laboratory Equipment
| Instrument | Analytical Purpose |
|---|---|
| LC‑MS/MS (ESI⁺) | [M + H]⁺ = 394.23 → 322.22 m/z transition confirmation. |
| HPLC‑DAD (220 nm) | Purity assessment — retention ~ 8.0 min on C18. |
| FTIR (ATR) | Diagnostic amide bands at 1655 cm⁻¹ and indole aromatic bands 1608 cm⁻¹. |
| UV–Vis Spectrophotometer | Quantitative λₘₐₓ ≈ 310 nm. |
| Analytical Balance (0.001 mg) | Microgram‑accurate sample quantification. |
| Refrigerated storage unit (–20 °C) | Prevents thermal and photo decomposition. |
Laboratory Consumables
- LC‑MS‑grade methanol & acetonitrile.
- Distilled water (≥ 18 MΩ cm).
- Amber autosampler vials with PTFE seals.
- PTFE syringe filters (0.22 µm).
- Nitrile or neoprene gloves, safety eyewear, lab coat.
- Antistatic spatulas and low‑bind Eppendorf tubes.
- Desiccant packs for long‑term storage stability.
Regulation & Safety
| Aspect | Information |
|---|---|
| Controlled Status | Schedule I / Class A analogue of LSD (EU · UK · US). |
| Permitted Use | Accredited research or forensic investigation only. |
| Signal Word (GHS) | DANGER |
| Hazard Statements | H300, H310, H330, H360 — Toxic if ingested / inhaled / skin contact; possible reproductive toxicant. |
| Precautionary Actions | P260, P280, P284, P501 — Use self‑contained ventilation, mandatory PPE, dispose via licensed hazmat channels. |
| Spill Procedure | Absorb with inert medium (vermiculite or carbon); seal for authorized elimination. |
| Transport Reference | UN 3462 — “Toxic solid, organic n.o.s.” |
Chemical Informatics
| Descriptor | Value |
|---|---|
| SMILES | CCN(CC)C(=O)N1C=C(C2CCCN3C2CC=C4C3=CN=C(C4)C(=O)N(CC)CC)C=C1 |
| InChIKey | VHKKXZPKBPBEEV‑UHFFFAOYSA‑N |
| Mol. Weight | 393.53 g mol⁻¹ |
| TPSA | 63 Ų |
| log P | 3.0 |
| Rotatable Bonds | 6 |
| Predicted Metabolism | N‑de‑diethylation → LSD formation. |
| Database Utility | Training data for QSAR ergoline binding and metabolic rate modelling. |
Compliance Notice
⚠️ Controlled Substance Advisory
1D‑LSD is classified as a Schedule I / Class A controlled substance analogue in most EU and U.S. jurisdictions.
Possession or distribution requires explicit research licensing and institutional ethical approval.This document is intended solely for scientific and forensic reference — not for advertising, promotion, or human use.
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