Buy O-Desmethyltramadol (O-DSMT) Powder Online
Chemical Composition and Properties
- Chemical Name: 3-(2-((Dimethylamino)methyl)-1-hydroxycyclohexyl)phenol
- Molecular Formula: C₁₅H₂₃NO₂
- Molecular Weight: 249.35 g/mol
- CAS Number: 73986-53-5
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in water, chloroform, and methanol
Biological Significance
Buy O-Desmethyltramadol (O-DSMT) is the primary active metabolite of tramadol, an opioid analgesic. It exhibits a higher affinity for the μ-opioid receptor compared to its parent compound, contributing significantly to tramadol’s analgesic effects. O-DSMT has been encountered as a designer drug and is associated with opioid-like effects, including analgesia and euphoria. However, its use carries risks such as respiratory depression, dependence, and overdose.
Regulatory Status and Safety Considerations
As of February 2026, O-DSMT is not approved for medical use in the United States and is classified strictly as a research chemical. In the United Kingdom, it was designated as a Class B drug under the Misuse of Drugs Act 1971 on February 26, 2013. Researchers must adhere to applicable laws and regulations when handling this compound.
Laboratory Handling and Equipment
When handling O-DSMT powder in a laboratory setting, it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles, to prevent inhalation, ingestion, and skin contact. Standard laboratory equipment such as fume hoods should be utilized to ensure a safe working environment. O-DSMT should be stored in a cool, dry place away from direct sunlight to maintain its stability.
Environmental Impact
There is limited information on the environmental impact of O-DSMT. As with all chemical compounds, proper disposal procedures should be followed to minimize potential environmental contamination.
Chemical Informatics
For computational chemistry applications, O-DSMT’s molecular structure and properties can be analyzed using various chemical informatics tools. Its IUPAC name is 3-(2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol, and it has a molecular weight of 249.35 g/mol.
Conclusion
O-Desmethyltramadol (O-DSMT) Powder is utilized in research settings to explore its pharmacological properties and potential therapeutic applications. Due to regulatory concerns and safety considerations, it is crucial to handle this compound with care and adhere to appropriate safety protocols in laboratory environments.




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