Buy 5‑MeO‑DMT Hydrochloride Powder Online

5-MeO-DMT Powder (Hydrochloride)

Name: 5-MeO-DMT Powder (Hydrochloride)
SKU: 234
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Category: Research Chemicals

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Buy 5‑MeO‑DMT Hydrochloride Powder Online –  (5‑Methoxy‑N,N‑Dimethyltryptamine) — Forensic & Research Reference

Buy 5‑MeO‑DMT Hydrochloride Powder is a naturally occurring tryptamine alkaloid found in several plant species (e.g., Virola, Anadenanthera) and in Bufo alvarius toad venom.
Synthetic versions have appeared in forensic seizures as off‑white crystalline powders.
Globally controlled under UN Psychotropic Convention (1971) Schedule I.

Organic / Inorganic Chemistry

Property	Description
IUPAC name	N,N‑dimethyl‑2‑(5‑methoxy‑1H‑indol‑3‑yl)‑ethan‑1‑amine
Molecular formula	C₁₃H₁₈N₂O
Molar mass	218.30 g·mol⁻¹
Functional groups	Indole nucleus, tertiary amine (N,N‑dimethyl), methoxy ether.
Physical form	Crystalline solid (white to tan).
Boiling point	~160 °C (at 10 mm Hg).
Solubility	Freely soluble in alcohols and chloroform; limited in water.
Reactivity	Oxidizes slowly in air or light to quinone‑like products.

Chemical Biology

Mechanism: High‑affinity partial agonist of 5‑HT₁A and 5‑HT₂A receptors.
Metabolism: O‑demethylation (→ Bufotenine); MAO‑mediated deamination; hydroxylation.
Duration in vivo: Short (10–40 min intrinsic half‑life in animal models).
Pharmacology: Profound alterations in perception and consciousness reported; no therapeutic license.
Toxicology: Data limited; immediate respiratory and cardiovascular monitoring required in clinical research.

Computational Chemistry

Descriptor	Typical Value (DFT B3LYP/6‑31G*)
HOMO–LUMO gap	4.7 eV
Dipole moment	2.2 D
Pred. log P	2.3
Polar surface area	41 Å²
Rotatable bonds	4
Indole dihedral angle	≈ 67° (Cα–Cβ–C3–N1).
Applications	SAR and CB‑visualization studies for indole‑based ligands.

Environmental Chemistry

- Persistence: Moderate; indolic core resists biodegradation.
- Degradation: Photo‑oxidation yielding methoxyindole quinones.
- Water treatment: Effectively eliminated by ozonation or UV/H₂O₂ oxidation.
- Ecotoxicity: Limited data; predicted LC₅₀ to fish ≈ mg·L⁻¹ range.

Laboratory Equipment (for licensed analysis)

Instrument	Analytical Purpose
GC‑MS (EI)	Molecular ion m/z 218; fragments 130, 159, 188.
LC‑MS/MS	High sensitivity trace quantification (LOD < 1 ng/mL).
FTIR	Characteristic bands: 3400 (NH), 1610 (C=C), 1250 (C–O).
¹H/¹³C NMR	5‑OCH₃ 3.8 ppm; N,N‑CH₃ 2.2 ppm; indole H 6.9–7.4 ppm.
UV–Vis	λₘₐₓ ≈ 276 nm aromatic absorbance.

Facility requirements:
Controlled‑substance permit, secure storage cabinet, Class II fume hood, validated analytical balances.

Consumables

- HPLC‑grade methanol / water with 0.1 % formic acid.
- Amber vials (PTFE septa).
- PTFE filters (0.22 µm).
- Certified calibration standards (under DEA or Home Office licence).
- PPE: lab‐coat, gloves, eye protection.

Regulation & Safety

Category	Details
Controlled status	Schedule I (US CSA 21 CFR 1308.11(d)(1)); Class A (Poison Act UK); Schedule 9 (Australia).
Permitted use	Forensic or licensed clinical/animal research only.
GHS hazards	H301 (Toxic if swallowed), H331 (Toxic if inhaled), H370 (Organ damage).
Storage	≤ –20 °C in dark, locked, ventilated freezer.
Disposal	Complete incineration via licensed hazard‑waste facility.

Chemical Informatics

Descriptor	Representative Value
SMILES	`CN(C)CCC1=CNC2=CC=C(OC)C=C12`
InChIKey	`RJKCGSCWXOLVMB‑UHFFFAOYSA‑N`
Molecular weight	218.30 g mol⁻¹
log P (pred)	2.3
TPSA	41 Å²
Applications	Chemical informatics modeling, metabolomics, mass‑spectral reference libraries.

Ethical and Legal Notice

⚠️ Controlled‑Substance Warning
5‑MeO‑DMT is internationally scheduled under the 1971 UN Psychotropic Convention.
Its production, sale, and possession without proper authorization are illegal.
This material is provided solely for scientific, environmental, and forensic documentation to aid compliance and analytical verification.