S4 Powder (Andarine)

Buy S4 Powder (Andarine) Online

Buy S4 Powder (Andarine), commonly known as Andarine, is a synthetic nonsteroidal selective androgen receptor modulator (SARM) developed for research into androgen receptor (AR) signaling. Available in various forms, including powder, Andarine is intended strictly for scientific research and analytical purposes.

Chemical Composition and Properties

• Chemical Name: (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
• Molecular Formula: C₁₉H₁₈F₃N₃O₆
• Molecular Weight: 441.36 g/mol
• CAS Number: 401900-40-1
• Appearance: Pale yellow fine powder
• Melting Point: Approximately 70–74°C
• Solubility: Soluble in DMSO (≥85 mg/mL), ethanol (≥85 mg/mL); poorly soluble in water (<1.2 mg/mL)
• Storage Conditions: Store at -20°C in a dry, dark environment

These properties are crucial for researchers to consider when designing experiments and handling the compound.

Mechanism of Action

Andarine functions as a selective agonist of the androgen receptor. In experimental systems, AR activation by S-4 is associated with:

• Modulation of anabolic signaling pathways in skeletal muscle
• Investigation of bone-related androgen signaling
• Comparative analysis of partial agonist behavior versus other SARMs

Unlike steroidal androgens, S-4 is studied for its nonsteroidal scaffold and tissue selectivity, making it a frequent subject of SARM structure–activity relationship (SAR) research.

Laboratory Equipment and Consumables

When conducting research with S-4 powder, it’s essential to utilize appropriate laboratory equipment and consumables to ensure accurate and safe experimentation. This includes:

• Precision balances for weighing
• Solvent-resistant containers for dissolution
• Personal protective equipment (PPE) such as gloves and safety goggles
• Proper storage solutions, like desiccators and temperature-controlled environments, to maintain the compound’s stability

Regulation and Safety

S-4 (Andarine) is not approved for human or veterinary use and is supplied strictly for laboratory and analytical research purposes. Researchers using it in laboratory contexts should observe:

• Protective equipment when handling powders
• Proper ventilation and storage per Material Safety Data Sheet (MSDS)
• Careful documentation of doses and observations
• Monitoring for hepatic, visual, and metabolic effects if used in controlled animal studies

One of the most distinctive safety concerns associated with S-4 involves its impact on vision. Users have reported yellow-tinted vision, difficulty adjusting to low-light environments, and symptoms resembling night blindness. These effects are believed to be dose-dependent and linked to Andarine’s interaction with androgen receptors in ocular tissue. While typically reversible after discontinuation, such visual disturbances may pose safety risks during activities such as driving or operating machinery in low-visibility conditions.

Chemical Informatics

Utilizing chemical informatics tools can aid researchers in understanding S-4’s properties, interactions, and potential applications. Databases such as PubChem provide comprehensive information on chemical structures, biological activities, safety, and toxicity data. These resources are invaluable for designing experiments and predicting outcomes.

Environmental Considerations

Proper disposal of S-4 and related materials is crucial to prevent environmental contamination. Laboratories should adhere to local regulations regarding hazardous waste disposal. This includes:

• Neutralizing solutions
• Using designated waste containers
• Contracting certified disposal services

Conclusion

S-4 (Andarine) powder offers a promising avenue for research into muscle growth and bone density enhancement. However, due to its potent biological activity and regulatory status, it is imperative that researchers handle this compound with caution, adhere to safety protocols, and stay informed about legal considerations.