5-MMPA (Mephedrene) Powder

€28

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Buy 5-MMPA (Mephedrene) Powder Online –  (5‑Methyl‑Methoxyphenyl‑2‑aminopropane, “Mephedrene”) — Scientific Reference

Buy 5-MMPA is a ring‑substituted phenethylamine belonging to the amphetamine analogue group.
It is sometimes encountered as a powder in forensic casework.
All handling is limited to accredited analytical facilities for toxicology or chemical‑profiling studies.

Organic / Inorganic Chemistry

Property	Description
IUPAC name	1‑(5‑methoxy‑2‑methylphenyl)‑2‑aminopropane (HCl salt often used analytically)
Formula	C₁₁H₁₇NO
Molar mass	179.26 g · mol⁻¹
Functional groups	Primary amine (–NH₂ / –NH₃⁺ in salt), aromatic ether (–OCH₃), alkyl methyl substitution
Physical form	White to off‑white crystalline powder; soluble in polar solvents.
Organic reactivity	Base forms salts with acids; prone to oxidative deamination and O‑demethylation.
Inorganic behavior	Forms HCl or HBr salts for stability in reference standards.

Chemical Biology

Mechanistic interest (academic): analogous to amphetamine; in silico models suggest interaction with monoamine transporters.
Biomedical status: no approved medical use; investigation restricted to licensed toxicology programs.
Metabolism: cytochrome P450 (O‑demethylation, β‑oxidation, deamination).
Toxicology: central nervous stimulation, hyperthermia, cardiovascular stress predicted from related analogues.

Computational Chemistry

Parameter	Typical Result (DFT B3LYP/6‑31G*)
Optimized geometry	Planar aromatic ring; alkyl amine side‑chain dihedral ≈ 64°.
HOMO–LUMO gap	≈ 4.5 eV (chemically stable aromatic amine).
Dipole moment	2.1 D.
Pred. log P	2.6 → moderate lipophilicity.
Polar surface area	32 Å².
In silico use	Training compound for SAR/QSAR datasets; energy minimization reference for phenethylamines.

Environmental Chemistry

- Persistence: Aromatic ring resistant to biodegradation.
- Transformation: Photo‑oxidation ↦ anisaldehyde and phenolic fragments.
- Soil/water partition: Moderate hydrophobicity (log Kow 2 – 3); adsorbs to organic matter.
- Removal: Advanced oxidation (ozonation / UV‑H₂O₂); high‑temp incineration > 1000 °C for solid residues.

Laboratory Equipment (for Authorized Analysis)

Instrument	Purpose
GC‑MS / LC‑MS/MS	Confirm m/z 180 [MH⁺]; quantify in forensic specimens.
FTIR / Raman	Bands: N–H stretch ~3400 cm⁻¹, Ar–O–CH₃ ~1250 cm⁻¹, C=C ~1600 cm⁻¹.
¹H / ¹³C NMR	Assign methoxy (3.8 ppm), methyl (2.2 ppm), amine side‑chain (2.8–1.0 ppm).
UV–Vis	λₘₐₓ ≈ 275 nm (π→π*).

Facility standards:
– Class II biosafety cabinet or fume hood.
– 0.1 mg analytical balance.
– Controlled‑substance‑approved storage unit.

Consumables

- Certified LC solvents (methanol, acetonitrile).
- PTFE syringe filters (0.22 µm).
- Amber autosampler vials with PTFE septa.
- Reference standards (DEA / Home Office licensed).
- Calibrated pipettes and weighing boats.
- Personal protective equipment (PPE): lab coat, nitrile gloves, goggles.

Regulation & Safety

Category	Description
Controlled status	Analogue of methamphetamine / cathinone family; Schedule I (US), Class B / C (UK); EU‑wide control under NPS legislation.
Use authorization	Forensic / regulatory analysis only; no clinical or consumer applications.
GHS hazards	H301 (Toxic if swallowed), H331 (Toxic if inhaled), H370 (Causes organ damage).
PPE	Laboratory coat, nitrile gloves, respiratory protection (P3 filter), eye protection.
Storage	Locked controlled‑substance freezer (≤ –20 °C), away from oxidizers and light.
Disposal	Licensed hazardous‑waste incineration; documented chain of custody.

Chemical Informatics

Parameter	Representative Value
SMILES	`CC(CN)C1=CC(OC)=C(C)C=C1`
InChIKey	`XPHYJZKRVFSTEK‑UHFFFAOYSA‑N`
Molecular weight	179.26 g mol⁻¹
Top. polar surface area	32 Å²
Rotatable bonds	3 – 4
Informatics applications	Toxicological QSAR sets, forensic mass spectral libraries, machine‑learning training on amphetamine analogues.

Ethical and Legal Notice

⚠️ Compliance Statement:
5‑MMPA (mephedrene) is a controlled substance analogue.
Its production, distribution, or use outside licensed forensic or research settings is illegal.
This document exists exclusively to aid scientific, analytical, and environmental understanding under relevant drug‑control and occupational safety regulations.