3-FA Pellets 50mg

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Buy 3‑FA Pellets 50mg Online  — Analytical Reference Material

3‑Fluoroamphetamine (buy 3‑FA pellets 50mg) is a halogenated amphetamine analogue of amphetamine and para‑fluoroamphetamine (PFA).
The compound serves as an analytical reference standard for forensic toxicology, LC–MS calibration, and comparative studies on halogen substituents in phenethylamine frameworks.

The 50 mg pelletized form provides fixed‑mass, easy‑handling standards for micro‑scale sample preparation and analytical reproducibility.

Organic / Inorganic Chemistry

Property	Information
IUPAC Name	1‑(3‑fluorophenyl)propan‑2‑amine
Molecular Formula	C₉H₁₂FN
Molecular Weight	153.20 g mol⁻¹
Chemical Class	Fluorinated amphetamine derivative
Functional Groups	Primary amine, aromatic fluoro substitution
Physical Appearance	White to off‑white pellet (50 mg nominal mass)
Melting Point (HCl salt)	≈ 156 – 160 °C
Boiling Point (free base)	≈ 203 °C (decomposes)
Solubility	Good in methanol, acetonitrile; limited in water (~6 mg mL⁻¹)
Stability	Stable at ≤ 25 °C in dark, dry conditions; degrades under UV light.

Chemical Biology

Pharmacological Family: Amphetamine‑type amine analogue.
Research Applications: Used to validate spectroscopic and chromatographic methods for fluorinated substituted amphetamines.
In vitro Metabolism: N‑deamination, β‑hydroxylation, aromatic hydroxylation, and fluoride ion release under strong oxidative conditions.
Enzymatic Profile: Reduced oxidation by CYP2D6 due to meta‑fluoro position → enhanced metabolic stability.
Toxicological Calibration: Applied for comparing LC–MS/MS fragmentation patterns among halogenated amphetamines.

Computational Chemistry Descriptors

Parameter	Predicted Value (B3LYP/6‑31G*)
Dipole Moment	2.70 D
HOMO–LUMO Gap	6.3 eV
log P (pred.)	2.3
pKa (amine)	9.8
Topological Polar Surface Area (TPSA)	26 Å²
Rotatable Bonds	3
Predicted Binding (DAT)	≈ –8.0 kcal mol⁻¹
Commentary: Fluoro substitution at the meta position modifies electron density across the ring, altering receptor affinity in computational models.

Environmental Chemistry

Hydrolytic Stability: Stable in neutral solutions for > 30 days (25 °C).
Photolysis: Moderate UV decay rate; half‑life ~ 5–6 h at 280 nm.
Biodegradability: Limited due to fluoroaryl structure.
Partition Coefficient: log Kow ≈ 2.3 (moderate bioaccumulation potential).
Waste Treatment: Oxidative neutralization (e.g., NaOCl or KMnO₄) prior to high‑temperature incineration (> 1100 °C).

Laboratory Equipment

Instrument	Analytical Use
LC–MS/MS	[M+H]⁺ = 154 m/z; major fragments 136 m/z, 119 m/z.
GC–MS (EI)	M⁺ = 153 m/z; base ion 44 (methylamine fragment).
FTIR (ATR)	Key peaks ≈ 3340 cm⁻¹ (N–H), 1220 cm⁻¹ (C–F).
¹H NMR (CDCl₃)	δ 7.0–7.4 (aromatic), 2.9–3.2 (CH₂–NH₂).
Handler Notes: Avoid moisture · Weigh in anti‑static conditions · Store ≤ –20 °C.

Consumables & Handling

LC‑grade methanol and acetonitrile.
0.1 % formic acid for MS mobile phases.
Amber vials with PTFE septa.
Analytical micro‑balance (±0.01 mg sensitivity).
PPE: nitrile gloves, coat, goggles, fume hood use mandatory.

Regulation & Safety

Aspect	Information
Controlled Status	Schedule I (U.S. Analogue Act) • Class B (UK MDA 1971) • Schedule 9 (Australia).
Permitted Use	Authorized forensic and toxicology research only.
GHS Signal Word	Danger
Hazard Phrases	H301, H311, H331 – Toxic if swallowed, in contact with skin, or inhaled.
Precautions	Avoid dust generation; handle under ventilation; wear PPE.
First Aid	Flush with water for ≥ 15 min · Seek medical attention immediately.
Waste Disposal	Collect in sealed labeled container for licensed incineration facility.

Chemical Informatics

Descriptor	Data
SMILES	`CC(CC1=CC(=CC=C1F))N`
InChIKey	`QXOWNYVXYZVGXQ‑UHFFFAOYSA‑N`
Formula Mass	153.20 g mol⁻¹
TPSA	26 Å²
log P	2.3
Rotatable Bonds	3
CAS Registry	Unassigned (as analogue substance)
Applications	Spectral database reference, QSAR training set entry, forensic compound cataloguing.

Legal & Ethical Statement

⚠️ Controlled‑Substance Notice
3‑Fluoroamphetamine is a regulated amphetamine analogue under international law. Possession or distribution outside licensed facilities is illegal.
This information is provided strictly for scientific documentation, toxicological awareness, and regulatory compliance, not for promotion or marketing.