3-FMA Powder

Name: 3-FMA Powder
SKU: 149
Availability: InStock

€23

Price is per gram

Category: Research Chemicals

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Buy 3‑FMA Powder  Online— Analytical Reference Standard

3‑Fluoromethamphetamine (Buy 3‑FMA Powder) is a fluorinated derivative within the phenethylamine/amphetamine chemical class.
It functions exclusively as a forensic mass‑spectral reference or instrument calibration compound for identifying fluorinated amphetamines.

In its powder form, the compound supports LC–MS/MS calibration, reference spectral libraries, and computational toxicology modeling.

Organic / Inorganic Chemistry

Property	Information
IUPAC Name	1‑(3‑fluorophenyl)‑N‑methylpropan‑2‑amine
Molecular Formula	C₁₀H₁₄FN
Molecular Weight	167.22 g mol⁻¹
Chemical Class	Fluoro‑substituted amphetamine
Functional Groups	Secondary amine, aromatic fluoro group, propyl side‑chain
Physical Form	White to off‑white crystalline powder
Melting Point (HCl)	≈ 159 – 163 °C
Solubility	Soluble in methanol, acetonitrile; moderate in water
Odor	Amine‑like
Stability	Stable if dry and protected from light; sensitive to oxidation under UV exposure

Chemical Biology

Pharmacological Class: Stimulant (amphetamine analogue); used only as a reference for transport assays and forensic identification.
Research Applications: LC–MS/MS and GC–MS method validation; transport mechanism comparison of halogenated amphetamines.
In vitro Metabolism: N‑demethylation, β‑hydroxylation, fluorophenyl ring oxidation.
Binding Insight: Fluoro‑substituent reduces oxidative metabolism and moderates lipophilicity vs methamphetamine.

Computational Chemistry

Descriptor	Predicted Value (B3LYP/6‑31G*)
Dipole Moment	2.73 D
HOMO–LUMO Gap	6.2 eV
log P (pred.)	2.7
pKa (amine)	9.8
TPSA	26 Å²
Rotatable Bonds	3
Docking Energy (DAT)	~ –8.2 kcal mol⁻¹
Interpretation: The meta‑fluoro group alters electrostatic potential and in silico binding orientation compared to para isomers.

Environmental Chemistry

Hydrolytic Stability: Resistant to hydrolysis in neutral pH.
Photolysis: Degrades moderately under UV light (254 nm exposure).
Biodegradability: Slow; fluoroaromatic ring resistant to microbial metabolism.
Bioaccumulation Potential: Moderate (log Kow ≈ 2.7).
Waste Treatment: Oxidative destruction (KMnO₄, NaOCl) before incineration > 1100 °C.

Laboratory Equipment

Instrument	Analytical Use
LC–MS/MS	[M+H]⁺ = 168 m/z; primary fragments 150, 119 m/z
GC–MS (EI)	M⁺ = 167 m/z; base peak 44 (methylamine fragment)
FTIR (ATR)	Key bands: C–F ≈ 1220 cm⁻¹, N–H ≈ 3300 cm⁻¹, C–N ≈ 1140 cm⁻¹
¹H NMR (400 MHz, CDCl₃)	Aromatic δ 7.0 – 7.4, CH₂ δ 2.9 – 3.2, CH₃ δ 2.2 – 2.4
Analytical Checks	Weight uniformity test ≤ ± 0.2 %; purity > 99 % (by HPLC)
Storage	Store sealed at –20 °C, dry, light‑protected environment

Consumables

LC/GC grade methanol & acetonitrile.
Formic acid (≥ 99 %, LC/MS quality).
Amber sample vials with PTFE/silicone septa.
Nitrile gloves, lab coat, and eye protection.
Static‑controlled workbench and micro spatulas.

Regulation & Safety

Aspect	Information
Controlled Status	Schedule I (US DEA Analogue Act coverage); Class B (UK MDA); Schedule 9 (Australia).
Permitted Use	Licensed research & law‑enforcement analytical work only.
GHS Signal Word	Danger
Hazard Phrases	H301 Toxic if swallowed; H311 Toxic in contact with skin; H331 Toxic if inhaled.
Precautionary Statements	Avoid dust generation; wear PPE; handle within fume hood.
First Aid	Flush exposed area ≥ 15 minutes; obtain immediate medical attention.
Waste Disposal	Send sealed waste container to licensed chemical destruction facility.

Chemical Informatics

Field	Data
SMILES	`CC(CC1=CC(=CC=C1)F)NC`
InChIKey	`CRYQINOUSPVWLC‑UHFFFAOYSA‑N`
Formula Mass	167.22 g mol⁻¹
TPSA	26 Å²
log P	2.7
Rotatable Bonds	3
CAS Number	1537‑49‑9
Use‑Case	Reference material for forensic method development and SAR/QSAR datasets.

Ethical and Legal Notice

⚠️ Controlled‑Substance Statement
3‑Fluoromethamphetamine is subject to national drug‑control legislation.
All possession, storage, and analysis require appropriate licenses and regulatory authorization.
This document is for scientific education, regulatory compliance, and cataloguing only and must not be used for commercial promotion or advertisement.