Buy 3‑FMA Powder Online— Analytical Reference Standard
3‑Fluoromethamphetamine (Buy 3‑FMA Powder) is a fluorinated derivative within the phenethylamine/amphetamine chemical class.
It functions exclusively as a forensic mass‑spectral reference or instrument calibration compound for identifying fluorinated amphetamines.
In its powder form, the compound supports LC–MS/MS calibration, reference spectral libraries, and computational toxicology modeling.
Organic / Inorganic Chemistry
| Property | Information |
|---|---|
| IUPAC Name | 1‑(3‑fluorophenyl)‑N‑methylpropan‑2‑amine |
| Molecular Formula | C₁₀H₁₄FN |
| Molecular Weight | 167.22 g mol⁻¹ |
| Chemical Class | Fluoro‑substituted amphetamine |
| Functional Groups | Secondary amine, aromatic fluoro group, propyl side‑chain |
| Physical Form | White to off‑white crystalline powder |
| Melting Point (HCl) | ≈ 159 – 163 °C |
| Solubility | Soluble in methanol, acetonitrile; moderate in water |
| Odor | Amine‑like |
| Stability | Stable if dry and protected from light; sensitive to oxidation under UV exposure |
Chemical Biology
- Pharmacological Class: Stimulant (amphetamine analogue); used only as a reference for transport assays and forensic identification.
- Research Applications: LC–MS/MS and GC–MS method validation; transport mechanism comparison of halogenated amphetamines.
- In vitro Metabolism: N‑demethylation, β‑hydroxylation, fluorophenyl ring oxidation.
- Binding Insight: Fluoro‑substituent reduces oxidative metabolism and moderates lipophilicity vs methamphetamine.
Computational Chemistry
| Descriptor | Predicted Value (B3LYP/6‑31G*) |
|---|---|
| Dipole Moment | 2.73 D |
| HOMO–LUMO Gap | 6.2 eV |
| log P (pred.) | 2.7 |
| pKa (amine) | 9.8 |
| TPSA | 26 Ų |
| Rotatable Bonds | 3 |
| Docking Energy (DAT) | ~ –8.2 kcal mol⁻¹ |
| Interpretation: The meta‑fluoro group alters electrostatic potential and in silico binding orientation compared to para isomers. |
Environmental Chemistry
- Hydrolytic Stability: Resistant to hydrolysis in neutral pH.
- Photolysis: Degrades moderately under UV light (254 nm exposure).
- Biodegradability: Slow; fluoroaromatic ring resistant to microbial metabolism.
- Bioaccumulation Potential: Moderate (log Kow ≈ 2.7).
- Waste Treatment: Oxidative destruction (KMnO₄, NaOCl) before incineration > 1100 °C.
Laboratory Equipment
| Instrument | Analytical Use |
|---|---|
| LC–MS/MS | [M+H]⁺ = 168 m/z; primary fragments 150, 119 m/z |
| GC–MS (EI) | M⁺ = 167 m/z; base peak 44 (methylamine fragment) |
| FTIR (ATR) | Key bands: C–F ≈ 1220 cm⁻¹, N–H ≈ 3300 cm⁻¹, C–N ≈ 1140 cm⁻¹ |
| ¹H NMR (400 MHz, CDCl₃) | Aromatic δ 7.0 – 7.4, CH₂ δ 2.9 – 3.2, CH₃ δ 2.2 – 2.4 |
| Analytical Checks | Weight uniformity test ≤ ± 0.2 %; purity > 99 % (by HPLC) |
| Storage | Store sealed at –20 °C, dry, light‑protected environment |
Consumables
- LC/GC grade methanol & acetonitrile.
- Formic acid (≥ 99 %, LC/MS quality).
- Amber sample vials with PTFE/silicone septa.
- Nitrile gloves, lab coat, and eye protection.
- Static‑controlled workbench and micro spatulas.
Regulation & Safety
| Aspect | Information |
|---|---|
| Controlled Status | Schedule I (US DEA Analogue Act coverage); Class B (UK MDA); Schedule 9 (Australia). |
| Permitted Use | Licensed research & law‑enforcement analytical work only. |
| GHS Signal Word | Danger |
| Hazard Phrases | H301 Toxic if swallowed; H311 Toxic in contact with skin; H331 Toxic if inhaled. |
| Precautionary Statements | Avoid dust generation; wear PPE; handle within fume hood. |
| First Aid | Flush exposed area ≥ 15 minutes; obtain immediate medical attention. |
| Waste Disposal | Send sealed waste container to licensed chemical destruction facility. |
Chemical Informatics
| Field | Data |
|---|---|
| SMILES | CC(CC1=CC(=CC=C1)F)NC |
| InChIKey | CRYQINOUSPVWLC‑UHFFFAOYSA‑N |
| Formula Mass | 167.22 g mol⁻¹ |
| TPSA | 26 Ų |
| log P | 2.7 |
| Rotatable Bonds | 3 |
| CAS Number | 1537‑49‑9 |
| Use‑Case | Reference material for forensic method development and SAR/QSAR datasets. |
Ethical and Legal Notice
⚠️ Controlled‑Substance Statement
3‑Fluoromethamphetamine is subject to national drug‑control legislation.
All possession, storage, and analysis require appropriate licenses and regulatory authorization.
This document is for scientific education, regulatory compliance, and cataloguing only and must not be used for commercial promotion or advertisement.




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