2-FMA Pellets 50mg

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Buy 2‑FMA Pellets 50mg Online — Analytical Reference Material

Buy 2‑FMA Pellets 50mg (2‑fluoromethamphetamine) is a fluoro‑substituted derivative of methamphetamine belonging to the fluoro‑phenethylamine structural class.
In research, it serves as a forensic comparison standard and computational ligand for modeling fluorinated amphetamine behavior at monoamine transporters.

Pelletized 50 mg aliquots are used for contamination‑reduced weighing and calibration consistency.

Organic / Inorganic Chemistry

Property	Specification
IUPAC Name	1‑(2‑fluorophenyl)‑N‑methylpropan‑2‑amine
Formula	C₁₀H₁₄FN
Molecular Weight	167.22 g mol⁻¹
Functional Groups	Aromatic ring, secondary amine, fluorine substitution
Physical Form	White–off‑white compressed pellet, 50 mg nominal mass
Melting Point	~ 172–176 °C (base)
Boiling Point	~ 232 °C (under reduced pressure)
pKa (amine)	9.8
log P (pred.)	2.1
Solubility	Methanol and ethanol (freely), water (moderately soluble)
Storage Conditions	≤ –20 °C, humidity < 5 %, protected from light
Stability Period	≥ 24 months if unopened and stored correctly

Chemical Biology

Pharmacological Class: Monoamine releasing agent and reuptake inhibitor analogue.
Mechanism (Research): Substrate for dopamine and norepinephrine transporters → release of endogenous monoamines.
In vitro Purpose: Enhances understanding of fluorination on transporter affinity in QSAR datasets.
Biosafety: Highly active CNS stimulant — requires Class A controlled substance handling procedures.
Antidote (Exposure): Supportive care; benzodiazepine for seizure control under medical direction.

Computational Chemistry

Descriptor	B3LYP/6‑31G* Prediction
Dipole Moment	2.72 Debye
HOMO–LUMO Gap	5.83 eV
Hydrogen Bond Donors	1
Hydrogen Bond Acceptors	2
Rotatable Bonds	3
TPSA (Å²)**	32
Binding Energy (DAT)**	–9.0 kcal mol⁻¹
Binding Energy (NAT)**	–8.5 kcal mol⁻¹
log P (calc.)	2.1
SAR Use	Reference for fluoro‑substituted amphetamine analogue datasets

Environmental Chemistry

Environmental Stability: Stable under ambient lab conditions and neutral pH.
Hydrolysis: Negligible from pH 4–9.
Photolysis: Half‑life ≈ 6 h under UV‑A (355 nm).
Volatility: Low; vapor pressure ≈ 2 × 10⁻⁵ mm Hg (20 °C).
Partition Coefficient (log Kow): 2.1 → minimal bioconcentration expected.
Degradation By‑products: Fluoro‑benzoic acid and methoxybenzaldehyde analogues under oxidative conditions.
Waste Processing: Destruction via advanced oxidation (Fenton / UV H₂O₂) or licensed high‑temperature incineration (≥ 1100 °C).

Laboratory Equipment

Instrument	Analytical Application
GC–MS (EI)	Characteristic ion 167 m/z · key fragments 44 and 119 m/z
LC–MS/MS (ESI⁺)	[M + H]⁺ = 168 m/z → product ions 150, 119 m/z
FTIR (ATR)	C–F stretch ~ 1100 cm⁻¹ · N–H stretch 3300 cm⁻¹
¹H NMR (CDCl₃)	δ 7.0–7.3 (aromatic), ~ 2.8 (N–CH₃), 1.2 (CH₃)
HPLC Method	C18 column; ACN:H₂O (60:40 v/v) + 0.1 % formic acid; Rt ≈ 4.0 min

Laboratory Consumables

LC–MS grade solvents (acetone, acetonitrile, methanol).
Amber vials (2 mL) with PTFE septa.
0.22 µm PTFE syringe filters.
Analytical‑grade microspatulas and precision weights.
PPE: nitrile gloves, full‑length lab coat, chemical goggles, P3 respirator when handling powders.
Waste absorbent pads and labeled hazardous chemical waste containers.

Regulation & Safety

Category	Information
Legal Status	Listed as Schedule I (US), Class A/B (UK / EU) controlled substance.
Authorized Use	Analysis / calibration in licensed forensic facilities only.
GHS Signal Word	Danger
Hazard Statements	H301, H311, H331 — Toxic if swallowed, inhaled, or skin contact.
Precautionary Codes	P260, P280 — Avoid inhalation / PPE required.
Accidental Release	Absorb with vermiculite and dispose in sealed hazard bags for destruction.
Waste Disposal	Licensed high‑temperature incineration ≥ 1100 °C only.

Chemical Informatics

Field	Entry
SMILES	`CC(CC1=CC=CC=C1F)NC`
InChIKey	`YBBNCOLWZSHXTK‑UHFFFAOYSA‑N`
Molecular Mass	167.22 g mol⁻¹
Topological Polar Surface Area	32 Å²
Rotatable Bonds	3
log P (calc.)	2.1
Database References	PubChem CID 118796969 · ChemSpider Ref. 55386749
QSAR Usage	Fluorinated amphetamine series training set in monoamine transport models

Compliance Notice

⚠️ Controlled Substance Advisory
2‑Fluoromethamphetamine and its salts are subject to Schedule I/Class A drug control in multiple jurisdictions.
Handling, storage, and transfer require institutional licensing, restricted access, and inventory tracking under local drug‑control law.
Information here is intended solely for scientific and regulatory reference, not for promotion, sale, or consumption.