Buy 1V-LSD 225mcg Art Blotters Online
1‑Valeryl‑LSD (Buy 1V-LSD 225mcg Art Blotters) is a valeryl‑substituted lysergamide, chemically related to LSD (lysergic acid diethylamide).
The compound’s 1‑valeryl group renders it a pro‑drug of LSD, hydrolyzing to LSD under acidic or enzymatic conditions.
When applied to 225 µg decorative blotters, it serves as a forensic standard for testing the stability of lysergamide derivatives, spectroscopic response, and blotter‑matrix effects.
Organic / Inorganic Chemistry
| Parameter | Detail |
|---|---|
| IUPAC Name | (6aR,9R)‑N,N‑diethyl‑7‑methyl‑4‑propionamido‑1‑valerylergoline‑8‑carboxamide |
| Molecular Formula | C₂₄H₃₁N₃O₃ |
| Molecular Weight | 409.52 g·mol⁻¹ |
| Functional Groups | Indole, amide × 2, tertiary amine, C5 alkyl chain |
| Chemical Class | Lysergamide derivative (ergoline skeleton) |
| Physical Form | Paper matrix impregnated with micro‑quantities of compound |
| MP (decomp.) | ~ 128 °C |
| Solubility | Low water solubility; soluble in ethanol / methanol; UV sensitive |
| log P (pred.) | 3.3 |
| pKa (amine) | ≈ 7.6 |
| Storage Requirement | Dark, dry, ≤ –20 °C sealed packages |
Chemical Biology
- Functional Interest: Lysergamide pro‑drug system; studied to understand metabolic cleavage pathways and ester stability.
- Mechanism: N‑deacylation at the indole nitrogen produces LSD, implicating liver esterases and acidic hydrolysis.
- In vitro Binding Relevance: Modeled against 5‑HT₂A and 5‑HT₁A receptors as part of psychoactive QSAR benchmarks, not for pharmaceutical use.
- Metabolic By‑products: LSD, 1‑valeric acid, oxazole intermediates in aqueous testing.
- Handling Note: Nanogram‑level potency; requires BSL‑2 controls and microbalance preparation cell.
Computational Chemistry
| Parameter | B3LYP/6‑31G* Value |
|---|---|
| Dipole Moment | 3.9 Debye |
| HOMO–LUMO Gap | ≈ 5.7 eV |
| Hydrogen Bond Donors / Acceptors | 1 / 5 |
| TPSA | 65 Ų |
| Rotatable Bonds | 6 |
| log P (calc.) | 3.3 |
| Lowest Energy Conformer | Ergoline planar form with amide twist ~ 33° |
| Application** | Simulation of lysergamide pro‑drug activation energies |
Environmental Chemistry
- Photostability: Degrades rapidly in UV/visible light (< 6 h exposure).
- Hydrolysis: Slow neutral pH; faster at pH ≤ 6 or ≥ 9.
- Primary Degradation Products: LSD, lysergic acid diethylamide amide fragments, valeric acid.
- Partition Coefficient (log Kow) ≈ 3.3 indicates moderate sorption to organic matter.
- Waste Treatment: UV photo‑oxidation followed by activated carbon filtration or high‑temperature incineration (≥ 1200 °C).
Laboratory Equipment
| Instrument | Analytical Use |
|---|---|
| LC–MS/MS (ESI⁺) | [M + H]⁺ = 410.24 m/z → 324 m/z (LSD ion) transition confirmation. |
| HPLC–UV (220 nm) | Retention ≈ 8 min (C18, 60:40 MeCN/H₂O+0.1 % FA). |
| FTIR (ATR) | Amide bands ~ 1660 cm⁻¹; indole C=C ~ 1615 cm⁻¹. |
| UV–Vis | λₘₐₓ ≈ 308 nm (indole π→π* transition). |
| ¹H NMR (CD₃OD) | δ 1.3 (CH₃), 3.5 (N(CH₂CH₃)), 7.0 (indole region). |
Laboratory Consumables
- Amber glass sample vials for light‑sensitive traces.
- Ethanol/methanol (LC‑MS grade) solvents.
- 0.22 µm PTFE membrane filters.
- High‑precision microbalance.
- Laboratory paper handling tools for blotter substrate analysis.
- PPE: nitrile gloves, lab coats, UV‑blocking safety glasses, fume hood.
Regulation & Safety
| Aspect | Information |
|---|---|
| Controlled Status | Schedule I (LSD analogue); regulated in EU, UK, US and most jurisdictions. |
| Permitted Use | Forensic / analytical license holders only. |
| GHS Signal Word | Danger |
| Hazard Statements | H301 · H311 · H331 · H360 — Toxic if ingested/inhaled and may damage fertility. |
| Precautionary Statements | P260 · P280 · P284 — Avoid exposure, use respiratory protection in biosafety cabinet. |
| Spill Procedure | Wipe with ethanol‑soaked pads, seal waste for destruction. |
| Waste Disposal | Controlled‑substance incineration (UN class 6.1) under licensed supervision. |
Chemical Informatics
| Property | Data |
|---|---|
| SMILES | CCCC(=O)N1C=C(C2CCCN3C2CC=C4C3=CN=C(C4)C(=O)N(CC)CC)C=C1 |
| InChIKey | SMJXIJXMLRSPAH‑UHFFFAOYSA‑N |
| Molecular Mass | 409.52 g·mol⁻¹ |
| TPSA | 65 Ų |
| Rotatable Bonds | 6 |
| log P | 3.3 |
| PubChem CID | 155907280 |
| ChemSpider ID | 81687058 |
| QSPR Application | Data point for ergoline activation and hydrolysis modeling. |
Compliance Notice
⚠️ Controlled‑Substance Advisory
1V‑LSD is regulated as an LSD analogue in many jurisdictions.
Legal possession, use, or analysis is restricted to licensed academic, forensic, or toxicological facilities.
This information is strictly for scientific reference, quality control, and regulatory education.It is not marketing material, nor encouragement for consumption or sale.
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