GW-501516 (Cardarine) Capsules

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Chemical Composition and Properties

• Chemical Name: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid
• Molecular Formula: C₂₁H₁₈F₃NO₃S₂
• Molecular Weight: 453.5 g/mol
• CAS Number: 317318-70-0
• Appearance: Off-white solid
• Solubility: Soluble in DMSO (up to 45.35 mg/mL) and ethanol (up to 22.68 mg/mL)

Biological Significance

Buy GW-501516 (Cardarine) Capsules, commonly known as Cardarine, is a potent and selective agonist of the peroxisome proliferator-activated receptor delta (PPARδ). Activation of PPARδ by GW-501516 has been shown to increase the expression of the ATP-binding cassette transporter A1 (ABCA1), facilitating apolipoprotein A1-mediated cholesterol efflux in vitro. In vivo studies have indicated that GW-501516 can elevate serum high-density lipoprotein (HDL) cholesterol levels and reduce small, dense low-density lipoprotein (LDL) levels in models of obesity.

Regulatory Status and Safety Considerations

GW-501516 is intended for research and development purposes only and is not approved for human or veterinary use. It is classified as a research chemical and is not intended for human consumption. The World Anti-Doping Agency (WADA) has prohibited the use of GW-501516 in competitive sports due to its performance-enhancing effects. Safety data sheets indicate that GW-501516 is not classified as hazardous under the 2012 OSHA Hazard Communication Standard.

Laboratory Handling and Equipment

When handling GW-501516 capsules in a laboratory setting, it is essential to:

• Personal Protective Equipment (PPE): Wear appropriate PPE, including gloves, safety goggles, and lab coats, to prevent inhalation, ingestion, and skin contact.
• Engineering Controls: Utilize fume hoods and ensure proper ventilation to minimize exposure to dust or vapors.
• Storage: Store the compound at -20°C in a tightly closed container, in a dry and well-ventilated place.

Environmental Impact

There is limited information on the environmental impact of GW-501516. As with all chemical compounds, proper disposal procedures should be followed to minimize potential environmental contamination.

Chemical Informatics

For computational chemistry applications, GW-501516’s molecular structure and properties can be analyzed using various chemical informatics tools. Its IUPAC name is 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid, and it has a molecular weight of 453.5 g/mol.

Conclusion

GW-501516 (Cardarine) Capsules are utilized in research settings to explore their pharmacological properties and potential therapeutic applications. Due to regulatory concerns and safety considerations, it is crucial to handle this compound with care and adhere to appropriate safety protocols in laboratory environments.