Buy Coluracetam (Vega Caps) 20mg Online — High‑Purity Racetam Reference Standard for Laboratory Research
Overview
Buy Coluracetam (Vega Caps) 20mg is a pyrrolidone‑based racetam derivative structurally classified as an acetamide nootropic analog, featuring a quinolinone skeleton substituted with a dimethylaminoethyl side chain.
The 20 mg Vega Caps formulation provides uniform, research‑grade capsules that contain 20 mg of Coluracetam (≥ 99% HPLC purity), standardized for spectroscopic, chromatographic, and computational reference purposes under laboratory conditions.
⚠️ For analytical and in‑vitro research only. Not for human consumption, therapeutic application, or clinical use.
Chemical Identity
- IUPAC Name: N‑(2,3‑dimethyl‑5,6,7,8‑tetrahydro‑1‑oxo‑1H‑benz[g]indol‑3‑yl)‑2‑(dimethylamino)acetamide
- Synonyms: Coluracetam; MKC‑231; BAM‑1110
- Chemical Class: Racetam / Pyrrolidone / Quinolinone hybrid compound
- Molecular Formula: C19H23N3O3
- Molecular Weight: 341.40 g/mol
- Purity: ≥ 99.0 % (by HPLC / NMR)
- Form: 20 mg capsules (Vega Caps)
- Appearance: Pale yellow to off‑white powder in two‑piece capsule
- Grade: Analytical / laboratory reference standard
Applications Across Chemistry Disciplines
Organic & Inorganic Chemistry
- Possesses both amide and tertiary amine groups — ideal for amide hydrolysis kinetics, amide‑to‑acid derivatization, and H‑bond donor/acceptor analysis.
- The quinolinone heterocycle serves as a model for studying π–π conjugation, aromatic substitution, and hydrogen bonding in heteroaromatic systems.
- Applicable in photochemical and redox mechanism studies due to aromatic C=O chromophore.
- In inorganic chemistry, functions as a potential ligand in simulation of transition metal–amide complexes and coordination chemistry studies.
Chemical Biology
- Serves as a reference ligand for simulation of neurotransmitter transport analogs (non‑biological models).
- Used in enzyme kinetic assays modeling acetylcholine biosynthetic and metabolic pathways (without biological testing).
- Applied in lipid membrane partition and diffusion simulations, highlighting amphiphilic and aromatic interactions.
- Excellent for pH stability profiling and in‑vitro oxidative degradation pathway mapping studies.
Computational Chemistry
- Benchmark molecule for Density Functional Theory (DFT) and MO (Frontier Orbital) calculations involving nitrogen–oxygen conjugation.
- Suitable for Molecular Dynamics (MD) simulations assessing conformational flexibility of amide linkages.
- Commonly employed in QSAR and QSPR datasets to predict lipophilicity (log P), dipole moment, and solvation energy.
- Used in pharmacophore modeling and quantum descriptor generation for racetam analog libraries.
Environmental Chemistry
- Model compound for heterocyclic amide persistence and hydrolytic degradation rate studies.
- Supports environmental fate analysis of pharmaceutical residues in wastewater and surface waters.
- Applicable to photolytic and oxidative aging experiments for advanced oxidation process (AOP) calibration.
- Utilized as a trace analytical standard for LC–MS/MS pollutant detection method validation.
Laboratory Equipment & Consumables
Recommended Analytical Instruments
- HPLC / LC–MS/MS systems — quantitative purity & retention time analysis
- FTIR spectrometer — amide (1650 cm⁻¹) and C=O (1720 cm⁻¹) stretch identification
- ¹H / ¹³C NMR spectrometer — ring current shift and functional group confirmation
- UV–Vis spectrophotometer — absorbance profile (~325 nm n→π* band)
- Thermogravimetric Analyzer (TGA) / DSC — stability testing under heat stress
Essential Laboratory Consumables
- Analytical grade solvents: methanol, ethanol, acetonitrile, dimethyl sulfoxide
- Amber vials with PTFE caps; glove protection (ISO certified nitrile)
- Desiccator cabinet for humidity control
- Calibrated pipettes and class‑A glassware for pellet or capsule disintegration testing
Regulation & Safety
Regulatory Status
- For research and analytical purposes only; not approved as a dietary, nutraceutical, or pharmaceutical product.
- Compliance required with REACH, OSHA HazCom, and CLP Regulations.
- Verify jurisdictional classification prior to import or laboratory storage.
Hazard Classification (Indicative GHS)
⚠️ Irritant (Category 2)
⚠️ Eye Irritation (Category 2A)
⚠️ Aquatic Chronic Hazard (Category 3)
Safety Precautions
- Handle under controlled environments with fume hood ventilation.
- Wear appropriate Personal Protective Equipment (PPE): gloves, goggles, lab coat.
- Avoid contact with moisture and oxidizing agents.
- Dispose of materials via licensed chemical waste services under EPA and REACH protocols.
- Product accompanied by Safety Data Sheet (SDS) and Certificate of Analysis (CoA).
Chemical Informatics & Data Integration
- Distributed with SMILES, InChI, and InChIKey identifiers for LIMS and cheminformatics databases.
- Includes full set of molecular descriptors: molecular mass, TPSA, polarizability, rotatable bonds, H‑bond donor/acceptor count, and log P.
- Compatibility with ChemAxon, RDKit, Open Babel, KNIME, and Schrödinger Suite.
- Ideal for machine learning (ML) data training on structure–property relationships and QSAR frameworks.
- Metadata format supports FAIR data principles for multi‑lab interoperability.
Analytical Characterization
- Purity (HPLC): ≥ 99.0 %
- LC–MS/MS [M+H]⁺: m/z 342 ± 0.002
- ¹H NMR (400 MHz): chemical shifts matching literature reference
- IR (ATR): C=O amide stretch ~ 1655 cm⁻¹
- UV–Vis λmax: approx. 325 nm
- Melting Range: 125 – 128 °C
- Moisture Content: < 0.2 % (Karl Fischer)
Storage & Stability
- Store below 25 °C, in dry conditions away from light.
- Protect from oxidizing compounds and humidity.
- Use amber‑glass vials with tamper‑evident seals.
- Stable for 24 months under controlled laboratory conditions.
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