3-FPM Pellets 60mg

Name: 3-FPM Pellets 60mg
SKU: 151
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Category: Research Chemicals

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Buy 3‑FPM Pellets 60mg Online — Analytical Reference Material

Buy 3‑FPM Pellets 60mg is a fluorinated analog of phenmetrazine, belonging to the morpholine‑based stimulant family.
In analytical chemistry, it serves as a reference compound for mass‑spectral comparison, toxicology method validation, and SAR modeling of heterocyclic amine stimulants.
Pelletized form (e.g., 60 mg per unit) enables consistent mass reference when calibrating or validating micro‑weighing equipment.

Organic / Inorganic Chemistry

Property	Information
IUPAC Name	2‑(3‑fluorophenyl)‑3‑methylmorpholine
Molecular Formula	C₁₁H₁₄FNO
Molecular Weight	195.23 g mol⁻¹
Primary Functional Groups	Secondary amine, ether (morpholine ring), fluoroaromatic group
Physical Form	Solid pellets (pressed powder under controlled load to 60 mg ± 2 %)
Solubility	Freely soluble in organic solvents (methanol, ethanol, acetonitrile); partially in water.
Thermal Stability	Stable at ambient temperature if protected from UV and moisture.
Decomposition	Begins > 190 °C with amine oxidation.

Chemical Biology

Research Context: Models monoamine transporter releasing activity; used as forensic standard.
Metabolic Pathways (in vitro): N‑oxidation → lactam formation; aromatic hydroxylation; glucuronidation of ring metabolites.
Biological Interactions: Acts as dopamine and norepinephrine transporter substrate in controlled cell assays only.
Biosafety: Requires transaction and handling under controlled‑substance registration.

Computational Chemistry

Descriptor	Predicted Value (B3LYP/6‑31G*)
Dipole Moment	2.95 D
HOMO–LUMO Gap	5.8 eV
log P (pred.)	2.6
pKa (amine)	9.45
Topological Polar Surface Area (TPSA)	27 Å²
Rotatable Bonds	3
Partial Charge Distribution	Fluorine ring –δ enhances lipophilic surface; amine +δ region available for electrostatic binding.
Interpretation: Electron‑withdrawing fluorine lowers HOMO energy, resulting in reduced oxidative liability vs. phenmetrazine.

Environmental Chemistry

Persistence: Moderate stability in surface water (half‑life ~ 20 days aerobic).
Degradation Pathways: Oxidative deamination → carboxylic acid derivative; subsequent mineralization to CO₂ + NH₃.
Bioaccumulation Potential: Low to moderate (log Kow ≈ 2.6).
Treatment Methods: Advanced oxidation (Fenton process, ozonation) prior to incineration (> 1100 °C).
Environmental Hazards: Release prohibited under chemical waste legislation.

Laboratory Equipment

Instrument	Purpose
LC–MS/MS	[M+H]⁺ = 196 m/z; fragment 178 m/z (loss H₂O).
GC–MS (EI)	M⁺ = 195 m/z; base peak 44 (morpholine fragment).
FTIR (ATR)	N–H stretch ≈ 3320 cm⁻¹, C–F ≈ 1230 cm⁻¹, C–O–C ≈ 1050 cm⁻¹.
NMR (¹H, 400 MHz)	δ 7.0–7.3 (aromatic H), 3.2–3.8 (morpholine CH₂), 1.3–2.0 (aliphatic CH₃).
Storage Conditions	–20 °C, dry, light‑proof sealed container under N₂ or Ar.

Consumables

LC–MS‑grade methanol, acetonitrile, and formic acid.
Amber autosampler vials (PFA/PTFE septa).
Analytical balance precision weights (for pellet calibration check).
Disposable micro spatulas, anti‑static work surface, nitrogen purge desiccator.
Personal protective equipment (PPE) — nitrile gloves, lab coat, eye protection.

Regulation & Safety

Aspect	Information
Controlled Status	Class B (UK MDA 1971); Schedule I (US DEA Analogue Act coverage); Schedule 9 (Australia).
Usage Permission	Restricted to licensed analytical and academic facilities.
GHS Signal Word	Danger
Hazard Statements	H301 Toxic if swallowed • H311 Toxic in contact with skin • H331 Toxic if inhaled • H412 Harmful to aquatic life.
Precautionary Measures	Use fume hood, PPE, anti‑aerosol techniques.
First Aid	Flush exposure area 15 min, seek immediate care.
Waste Management	Send sealed pellets to licensed hazardous chemical destruction facility.

Chemical Informatics

Field	Data
SMILES	`CC1COC(CC2=CC(=CC=C2)F)N1`
InChIKey	`LALWYYOSOXQZQP‑UHFFFAOYSA‑N`
Formula Mass	195.23 g mol⁻¹
TPSA	27 Å²
log P	2.6
Rotatable Bonds	3
CAS Number	1350768‑28‑8
Laboratory Use	Forensic calibration standard, mass‑spectrometric reference, QSAR training input.

Legal & Ethical Notice

⚠️ Controlled Substance Statement
3‑Fluorophenmetrazine and its derivatives are classified under various national controlled substance laws.
All handling, storage, and transport must comply with relevant legislation and licensing requirements.
This technical summary is provided for forensic, regulatory, and academic purposes only and should not be interpreted as sales or advertising material.