Buy 1B-LSD 125mcg Blotters Online
Buy 1B-LSD 125mcg Blotters is a semi‑synthetic ergoline derivative and an N‑acylated lysergamide, differing from LSD by the replacement of the indole‑N¹ hydrogen with a butanoyl (–COCH₂CH₂CH₃) group.
The 125 µg blotter matrix allows consistent microgram‑level reference for chromatographic standardization and mass spectral calibration in forensic chemistry.
Organic / Inorganic Chemistry
| Property | Specification |
|---|---|
| IUPAC Name | (6aR,9R)‑N,N‑diethyl‑7‑methyl‑4‑(1‑butanoylamido)ergoline‑8‑carboxamide |
| Formula | C₂₅H₃₃N₃O₂ |
| Molecular Weight | 407.56 g·mol⁻¹ |
| Chemical Class | Lysergamide (indole ergoline alkaloid) |
| Functional Groups | Secondary indole, two amide moieties, tertiary amine |
| Physical State | Impregnated cellulose blotter (solid) |
| Appearance | White paper blotter square (typically 6–7 mm grid) |
| Solubility | Soluble in methanol and ethanol; low aqueous solubility |
| log P (calc.) | ≈ 3.0 |
| pKa (amine) | 7.3 |
| UV λₘₐₓ | ≈ 305–308 nm (indole transition) |
| Stability | Degrades under UV light and moisture; store in dark at ≤ –20 °C |
Chemical Biology
- Category: Lysergamide ergoline analogue.
- Biochemical Role: Hydrolyzes in acidic or enzymatic conditions to yield LSD and butyric acid.
- Analytical Use: Comparative control material for LSD identification in LC–MS and GC–MS.
- In Vitro Applications: Used in metabolite profiling and hydrolysis kinetic studies of acyllated indoles.
- Precaution: Microgram‑active compound — handle only in biosafety cabinet under licensed research authority.
Computational Chemistry
| Descriptor | Typical Value (B3LYP/6‑31G*) |
|---|---|
| Dipole Moment | 3.6 D |
| HOMO–LUMO Gap | 5.8 eV |
| Molecular Surface Area | ≈ 505 Ų |
| Topological Polar Surface Area (TPSA) | ≈ 63 Ų |
| Rotatable Bonds | 7 |
| Predicted log S | ≈ –3.7 |
| QSAR Use | Modeling lysergamide hydrolysis kinetics and structure–activity comparisons. |
Environmental Chemistry
- Photolysis: Rapid decomposition under UV (half‑life < 6 h).
- Hydrolysis: Breakdown to LSD in aqueous medium (pH 5–7 at 25 °C ≈ 48 h half‑life).
- Biodegradation: Incomplete (≈ 30–40 % mineralization in 28 days).
- Partition Coefficient (log Kow) ≈ 3 → low bioaccumulation potential.
- Waste Disposal: Neutralize with alkaline NaOCl solution and incinerate (≥ 1200 °C).
- Environmental Hazard: Organic toxicant; prevent release into aquatic systems.
Laboratory Equipment
| Instrument | Analytical Purpose |
|---|---|
| HPLC‑UV (305 nm) | Purity and quantification on C18 reversed phase. |
| LC–MS/MS ESI⁺ | [M + H]⁺ = 408.25 m/z; fragment 337.23 m/z (LSD core). |
| GC–MS (EI 70 eV) | Significant amidic fragment pattern for N‑butanoyl series. |
| FTIR (ATR) | C=O amide stretch ≈ 1652 cm⁻¹; C=C indole 1611 cm⁻¹. |
| UV‑Vis Spectrometer | Standard reference absorbance at ~305 nm. |
| Precision Balance (0.001 mg) | Mass uniformity‑testing of blotter segments. |
Laboratory Consumables
- LC/MS‑grade methanol, acetonitrile, water.
- Amber autosampler vials with PTFE/silicone septa.
- 0.2 µm PTFE syringe filters.
- Nitrile gloves, safety glasses, lab coat.
- Low‑lint forceps for blotter handling.
- Desiccant packs and foil bags for sealed storage.
- Certified pipette tips for microliter‑level solution preparation.
Regulation & Safety
| Parameter | Information |
|---|---|
| Controlled Status | Schedule I / Class A lysergamide analogue (EU Psychoactive Substances Act; US CSA). |
| Permitted Use | Forensic and academic research under licensed conditions. |
| GHS Signal Word | DANGER |
| Hazard Statements | H300, H310, H330 — Fatal if swallowed or inhaled; H361 — Suspected of reproductive toxicity. |
| Precautionary Statements | P260, P280, P284, P501 — Wear PPE, avoid exposure, dispose safely. |
| Transport Label | UN 3462: “Toxic solid, organic, n.o.s.” (Class 6.1) |
| Spill Procedure | Absorb with carbon material and incinerate in chemical waste facility. |
| Storage Conditions | Dark, ≤ –20 °C, in hermetically sealed amber vials. |
Chemical Informatics
| Descriptor | Value |
|---|---|
| SMILES | CCN(CC)C(=O)N1C=C(C2CCCN3C2CC=C4C3=CN=C(C4)C(=O)N1CCCC) |
| InChIKey | NJDWSDRPTVYDKV‑UHFFFAOYSA‑N |
| Molecular Weight | 407.56 g·mol⁻¹ |
| TPSA | 63 Ų |
| Rotatable Bonds | 7 |
| Predicted log P | ≈ 3.0 |
| Diagnostic m/z (ESI⁺) | 408 → 337 (LSD core fragment). |
| Informatics Application | QSAR/QSPR training set development for ergoline analogue libraries. |
Compliance Notice
⚠️ Legal & Safety Advisory
1B‑LSD is considered a Schedule I / Class A controlled substance analogue under the U.S. Controlled Substances Act, the U.K. MDA 1971, and EU drug control frameworks.
Possession, use, or distribution is restricted to licensed facilities only.This document is intended for scientific, analytical, and forensic reference—not advertising or promotion of psychoactive materials.
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