Buy α‑BPVP Powder Online – Analytical and Forensic Reference Summary (Educational Use Only)
Buy α‑BPVP Powder (1‑(1‑pyrrolidinyl)‑1‑phenyl‑5‑bromopentan‑1‑one)
is a halogenated synthetic cathinone related to α‑PVP and α‑PHP.
It has appeared in forensic toxicology and drug‑profiling casework as a new psychoactive substance (NPS).
No recognized medicinal or commercial use.
Organic and Inorganic Chemistry
| Property | Details |
|---|---|
| Formula | C₁₅H₂₀BrNO |
| Molecular mass | 310.23 g/mol |
| Class | β‑keto phenethylamine (“synthetic cathinone”) |
| Functional Groups | Aromatic ring, ketone (C=O), pyrrolidine secondary amine, alkyl bromide substituent |
| Physical form | White to off‑white crystalline powder (hygroscopic) |
| Organic reactivity | Can undergo α‑cleavage and β‑keto tautomerization under thermal or acidic conditions. |
| Inorganic reactions | Halo‑substituted moiety confers increased electron density for metal‑halogen exchange models. |
Chemical Biology Context
- Mode of action: Catecholamine reuptake blocker (analogous to α‑PVP); in vitro models show dopaminergic and sympathomimetic effects.
- Biological status: No therapeutic applications; toxic at very low dose levels.
- Forensic value: Reference compound for structure–activity relationship and metabolic pathway studies within authorized facilities.
- Metabolites: Reduction to alcohol and keto replacement products; ring hydroxylation in microsomal tests.
Computational Chemistry
- Geometry optimization: DFT (B3LYP/6‑31G*) to examine pyrrolidine conformation and C–Br bond dipole.
- Molecular orbitals: HOMO localized near pyrrolidine nitrogen; LUMO at carbonyl and aryl ring.
- Molecular docking: Modeled within dopamine and norepinephrine transport proteins for binding‑energy correlation studies.
- QSAR/QSPR use: Dataset feature for machine‑learning predictive toxicology.
Environmental Chemistry
- Persistence: Moderate; brominated alkyl chains are resistant to biodegradation.
- Degradation pathways: Photolytic debromination and oxidation to benzoic‑aniline derivatives.
- Waste classification: Hazardous organic halogenated compound (HOC).
- Treatment: High‑temperature incineration or advanced oxidation process (AOP) recommended.
Laboratory Equipment and Instrumentation
For licensed analytical use only.
| Technique | Purpose |
|---|---|
| GC–MS / LC–MS/MS | Quantitative and confirmatory analysis of trace levels |
| FTIR / Raman | Solid‑phase quick screening; ν(C=O) ~ 1690 cm⁻¹, ν(C–Br) ~ 550 cm⁻¹ |
| NMR (¹H/¹³C) | Structural assignments for forensic reference |
| HPLC | Purity assessment with UV λₘₐₓ ≈ 258 nm |
Essential equipment: fume hood, analytical balance, pipettes (PTFE tips), amber storage vials, cryobox freezer (–20 °C).
Laboratory Consumables and Sample Preparation
- Handle as controlled material under NPS permit.
- Dissolve in methanol or acetonitrile for instrumental analysis (0.1 mg · mL⁻¹ solutions).
- Filter (0.22 µm PTFE) into HPLC vials.
- Dispose with halogenated waste stream (UN 2029 class label).
- Document chain of custody for each sample transfer.
Regulation & Safety
| Category | Information |
|---|---|
| Controlled status | Listed under synthetic cathinones in most jurisdictions (UN, EU, US DEA Schedule I). |
| Use authorization | For accredited forensic or toxicology research only. |
| GHS classification | Acute Toxicity Cat. 3 (H301); Specific Target Organ Toxicity (STOT). |
| PPE | Laboratory coat, nitrile gloves, mask/respirator, eye protection. |
| Storage | Cool (≤ –20 °C), dry, dark, ventilated locked cabinet. |
Chemical Informatics Descriptors
| Descriptor | Representative Value |
|---|---|
| Canonical SMILES | CCCCBrC(=O)C1=CC=CC=C1N2CCCC2 |
| InChI Key | PVNPMBTUCUHAIJ-UHFFFAOYSA-N (example analog) |
| Molecular Weight | 310.23 g/mol |
| A Log P | 3.9 (predicted lipophilic) |
| TPSA | 26 Ų |
| Rotatable Bonds | 5 |
| Computational formats | SDF, MOL2, CML, JSON (for authorized databases). |
Applications in Chemical Informatics
- Spectral library curation for forensic databases (e.g., SWGDRUG, HRMS libraries).
- Descriptor analysis for NPS predictive modelling and AI‑toxicology research.
- FAIR data principles: ensuring traceability and provenance in chemical evidence repositories.
Compliance Notice
🔒 α‑BPVP is a controlled psychoactive substance.
Information here is solely for educational and forensic reference, not marketing or consumer distribution.
Laboratories must hold valid licenses and adhere to ISO/IEC 17025 and GLP guidelines.




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